International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, PR China; Department of Pathogenic Biology, Hebei Medical University, Shijiazhuang 050017, PR China.
Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang 050017, PR China.
Stem Cell Res. 2022 Oct;64:102907. doi: 10.1016/j.scr.2022.102907. Epub 2022 Sep 7.
Peripheral blood mononuclear cells (PBMCs) of a 38-year-old healthy female were isolated and reprogrammed into the induced pluripotent stem cells (iPSCs). The established iPSC line expressed various pluripotency stem cell markers and potential of differentiating into three germ layers, meanwhile maintained normal karyotype.
将一位 38 岁健康女性的外周血单个核细胞(PBMC)分离出来,并将其重编程为诱导多能干细胞(iPSC)。所建立的 iPSC 系表达各种多能干细胞标志物,并具有向三个胚层分化的潜能,同时保持正常核型。