From the Department of Internal Medicine, Radiology Division, Rabigh Medical College, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Saudi Med J. 2022 Sep;43(9):1057-1061. doi: 10.15537/smj.2022.43.9.20220346.
A cardiac myxoma is a rare tumor that could be incidental or present with common symptoms due to embolization. A minority of cases are attributed to carney complex, a rare inherited disease. A 73-year-old Asian male presented with acute left-side weakness, slurred speech, gait imbalance, and subacute constitutional symptoms. Left atrial myxoma was discovered by computed tomography and confirmed by echocardiography. Brain imaging revealed pituitary macroadenoma with subarachnoid and intraventricular hemorrages. The hormonal profile confirmed pituitary apoplexy, for which hormone replacement was initiated. Workup also revealed multiple endocrine tumors and excluded infection and malignancy. Myxoma resection could not be carried out, due to the patient's rapid clinical deterioration and death.Furthermore, the presence of cardiac myxoma, non-functioning pituitary macroadenomas, and pituitary apoplexy is extremely rare and rarely documented in the literature. Therefore, we emphasize clinical awareness of rare conditions with atypical presentations to improve outcomes.
心脏黏液瘤是一种罕见的肿瘤，可能是偶发的，也可能因栓塞而出现常见症状。少数病例归因于卡尼综合征，这是一种罕见的遗传性疾病。一名 73 岁的亚裔男性出现左侧无力、言语不清、步态失衡和亚急性全身症状。计算机断层扫描发现左心房黏液瘤，并通过超声心动图证实。脑成像显示垂体大腺瘤伴蛛网膜下腔和脑室出血。激素谱证实为垂体卒中，开始进行激素替代治疗。进一步检查还发现了多种内分泌肿瘤，排除了感染和恶性肿瘤。由于患者病情迅速恶化和死亡，无法进行心脏黏液瘤切除术。此外，心脏黏液瘤、无功能垂体大腺瘤和垂体卒中的存在极其罕见，在文献中很少有记载。因此，我们强调对表现不典型的罕见疾病的临床认识，以改善预后。
