Tao H, Xia S M, Chan Z Y, Song G, Yanagihara R
Intervirology. 1987;27(1):45-52. doi: 10.1159/000149714.
Three distinctive types of viral inclusion bodies were identified in hantavirus-infected cells by thin-section electron microscopy. The inclusion bodies, designated granular, granulofilamentous, and filamentous, were intracytoplasmic and closely associated with the rough endoplasmic reticulum and Golgi cisternae. Virus specificity of the inclusions was verified by immune colloidal gold and immunoperoxidase labeling. The inclusion bodies were a common morphological marker for 13 strains of hantaviruses studied, irrespective of their origin.
通过超薄切片电子显微镜在汉坦病毒感染的细胞中鉴定出三种不同类型的病毒包涵体。这些包涵体分别称为颗粒状、颗粒丝状和丝状，位于细胞质内，与粗面内质网和高尔基池紧密相关。通过免疫胶体金和免疫过氧化物酶标记验证了包涵体的病毒特异性。无论其来源如何，这些包涵体是所研究的13株汉坦病毒的常见形态学标志物。
