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臭氧消除根管生物膜内源性微生物的疗效

Efficacy of Ozone to Eliminate Endopathogenic Microorganism in Rootcanal Biofilm.

作者信息

Pawar Madhura, Agwan Muhammed Atif Saleem, Toshniwal Nandalal G, Biswas Krishna, Raina Rupshi, Pawar Swapnil

机构信息

Department of Pedodontics and Preventive Medicine, Dr. DY Patil Dental College and Hospital, Dr. DY Patil Vidyapeeth, Pune, Maharashtra, India.

Department of Restorative Dentistry, College of Dentistry in Alrass, Qassim University, KSA.

出版信息

J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S876-S879. doi: 10.4103/jpbs.jpbs_916_21. Epub 2022 Jul 13.

DOI:10.4103/jpbs.jpbs_916_21
PMID:36110706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9469337/
Abstract

OBJECTIVE

The researchers wanted to see whether ozonated water with ultrasonication and sodium hypochlorite can destroy bacteria in root canals.

MATERIALS AND METHODS

A total of 40 single-rooted human teeth were used. A total of 100 roots were harvested and mechanically prepared. The root canals were randomly divided into four classes ( = 10) after being infected with E. faecalis for 24 h. Each sample's MTT value was calculated.

CONCLUSIONS

NaOCl and aqueous ozone provide antibacterial effects in conditions in root canals.

摘要

目的

研究人员想了解经超声处理的臭氧水和次氯酸钠能否杀灭根管内的细菌。

材料与方法

共使用40颗单根人牙。总共收集了100个牙根并进行机械预备。将根管感染粪肠球菌24小时后随机分为四组（每组n = 10）。计算每个样本的MTT值。

结论

次氯酸钠和臭氧水在根管条件下具有抗菌作用。

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本文引用的文献

1
Antimicrobial effect of ozonated water, sodium hypochlorite and chlorhexidine gluconate in primary molar root canals.臭氧水、次氯酸钠和葡萄糖酸氯己定在乳磨牙根管中的抗菌作用
Eur J Dent. 2014 Oct;8(4):469-474. doi: 10.4103/1305-7456.143627.
2
The mysterious appearance of enterococci in filled root canals.粪肠球菌在根管充填后根管内的神秘出现。
Int Endod J. 2009 Apr;42(4):277-87. doi: 10.1111/j.1365-2591.2008.01537.x. Epub 2009 Feb 7.
3
Effectiveness of ozone against endodontopathogenic microorganisms in a root canal biofilm model.根管生物膜模型中臭氧对牙髓致病变微生物的有效性
Int Endod J. 2009 Jan;42(1):3-13. doi: 10.1111/j.1365-2591.2008.01460.x.
4
Clinical implications and microbiology of bacterial persistence after treatment procedures.治疗程序后细菌持续存在的临床意义及微生物学
J Endod. 2008 Nov;34(11):1291-1301.e3. doi: 10.1016/j.joen.2008.07.028. Epub 2008 Sep 17.
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The effect of exposure to irrigant solutions on apical dentin biofilms in vitro.体外接触冲洗液对根尖牙本质生物膜的影响。
J Endod. 2006 May;32(5):434-7. doi: 10.1016/j.joen.2005.07.002.
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Comparison of the antimicrobial activity of six irrigants on primary endodontic pathogens.六种冲洗剂对主要牙髓病原菌抗菌活性的比较。
J Endod. 2005 Jun;31(6):471-3. doi: 10.1097/01.don.0000148868.72833.62.
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Root canal disinfection: a review of concepts and recent developments.根管消毒：概念与最新进展综述
Aust Endod J. 2003 Aug;29(2):70-4. doi: 10.1111/j.1747-4477.2003.tb00515.x.
8
Clinical implications of the smear layer in endodontics: a review.牙髓病学中玷污层的临床意义：综述
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Dec;94(6):658-66. doi: 10.1067/moe.2002.128962.
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Biofilms: survival mechanisms of clinically relevant microorganisms.生物膜：临床相关微生物的生存机制
Clin Microbiol Rev. 2002 Apr;15(2):167-93. doi: 10.1128/CMR.15.2.167-193.2002.
10
Effects of rotary instrumentation and different etchants on removal of smear layer on human dentin.旋转器械和不同蚀刻剂对人牙本质玷污层去除的影响。
J Prosthet Dent. 2001 Jan;85(1):67-72. doi: 10.1067/mpr.2001.112792.