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来自猕猴桃内生真菌菌株的萜类化合物及其对青枯菌的抗菌活性。

Terpenoids from Kiwi endophytic fungus sp. and their antibacterial activity against pv. .

作者信息

Yu Jun-Jie, Wei Wen-Ke, Zhang Yu, Cox Russell J, He Juan, Liu Ji-Kai, Feng Tao

机构信息

School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, China.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.

出版信息

Front Chem. 2022 Sep 1;10:990734. doi: 10.3389/fchem.2022.990734. eCollection 2022.

Abstract

A chemical investigation on the kiwi endophytic fungus sp. Resulted in the isolation of eight new terpenoids (-) and five known analogues (-). Compounds - are novel sativene sesquiterpenoids containing three additional skeletal carbons, while compounds and are rare dimers. Compounds - and are sesterterpenoids that have been identified from this species for the first time. Compounds and showed antibacterial activity against kiwifruit canker pathogen pv. (Psa) with MIC values of 32 and 64 g/ml, respectively.

摘要

对猕猴桃内生真菌sp.进行的化学研究,分离出了8种新的萜类化合物(-)和5种已知类似物(-)。化合物-是含有三个额外骨架碳的新型檀香烯倍半萜类化合物,而化合物和是罕见的二聚体。化合物-和是首次从该物种中鉴定出的链状五萜类化合物。化合物和对猕猴桃溃疡病菌pv.表现出抗菌活性,其最低抑菌浓度(MIC)值分别为32和64μg/ml。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a30/9475172/1db6f0a5fabd/fchem-10-990734-g001.jpg

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