Sotiropulos Konstadinos, Kourkoutas Dimitrios, Almaliotis Diamantis, Ploumidou Katherine, Karampatakis Vasileios
Department of Ophthalmology, 417 Army Shared Fund Hospital, Athens11521, Greece.
Department of Ophthalmology, 401 Army General Hospital of Athens, Athens11525, Greece.
Int J Ophthalmol. 2022 Sep 18;15(9):1529-1537. doi: 10.18240/ijo.2022.09.17. eCollection 2022.
Stem cells are undifferentiated cells showcasing a remarkable capacity of self-replenishing and differentiating into mature cells. Their ability to proliferate connotes that a designated stem cell source is capable of generating an unrestricted number of mature cells. The ever-increasing comprehension of position, activity, and function of ocular stem cells has led to rapid progress and incessant improvement of possible procedures and therapies. A narrative review was conducted to summarize the current evidence on clinical trials and respective literature, regarding current evolution in the field of ocular regenerative medicine. We tried to ascertain the safety of experimental and clinical procedures, their effectiveness, and the ethical repercussion of their use.
干细胞是未分化的细胞，具有显著的自我更新和分化为成熟细胞的能力。它们的增殖能力意味着特定的干细胞来源能够产生数量不受限制的成熟细胞。对眼干细胞的位置、活性和功能的理解不断增加，推动了可能的程序和治疗方法的快速进展和持续改进。进行了一项叙述性综述，以总结关于眼再生医学领域当前进展的临床试验和相关文献的现有证据。我们试图确定实验和临床程序的安全性、有效性以及使用它们的伦理影响。
