Department of Pathology, Baylor Scott & White Health, Temple, TX, USA.
J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231181959. doi: 10.1177/23247096231181959.
Alveolar adenoma (AA) is a rare type of pulmonary neoplasm showing proliferation of alveolar epithelium and septal mesenchyme. Clinically, AA is asymptomatic, benign, and usually diagnosed incidentally. Surgical excision is curative. The etiology of AA is controversial and the pathogenesis is unknown, but it is thought to stem from type II pneumocytes and fibroblasts or fibroblast-like cells. The stromal cells in AA may show rare staining for CD34. Diffuse CD34 positivity of the interstitial stromal cells has rarely been described and reviewed. Here, we report a case of AA with strong and diffuse CD34 staining in the stromal cells.
肺泡腺瘤（AA）是一种罕见的肺肿瘤，表现为肺泡上皮和间隔间质的增生。临床上，AA 是无症状的良性肿瘤，通常为偶然发现。手术切除是治愈性的。AA 的病因存在争议，发病机制尚不清楚，但被认为起源于 II 型肺泡细胞和成纤维细胞或成纤维细胞样细胞。AA 中的间质细胞可能对 CD34 有罕见的染色。弥漫性 CD34 阳性的间质细胞很少被描述和回顾。在这里，我们报告了一例 AA 病例，其间质细胞中 CD34 染色强且弥漫。
