Coordenação Geral de Atenção às Pessoas com Doenças Crônicas, Ministério da Saúde, Brasília 70058-900, Brazil.
Programa de Pós-Graduação em Ciências e Tecnologias em Saúde, Universidade de Brasília, Brasília 72220-275, Brazil.
Nutrients. 2022 Sep 10;14(18):3736. doi: 10.3390/nu14183736.
Background: Postprandial glycemic excursions are associated with impairment control of diabetes mellitus. Long-term consumption of flaxseed can lower blood glucose levels; however, its effects on the postprandial glycemic response remain unknown. Therefore, this study aimed to evaluate the acute effects of raw flaxseed consumption on the 2 h postprandial glycemic curve in men with type 2 diabetes mellitus (T2DM). Methods: This was a randomized crossover clinical trial. Nineteen men with T2DM were randomly assigned a standardized breakfast without (control) or with a previous intake of 15 g of ground raw golden flaxseed (flax). Glycemia was measured at fasting and postprandial at 15, 30, 45, 60, 90, and 120 min. Palatability markers (visual appeal, smell, and pleasantness of taste) and taste intensity (sweetness, saltiness, bitterness, sourness, and creaminess) were evaluated. Results: The peak glucose rise and the 2 h AUC glycemic response reduced in the flax group by 17% (p = 0.001) and 24% (p < 0.001), respectively. The glucose peak time, palatability, and taste parameters did not differ between the two groups. Conclusions: Ingestion of 15 g of ground raw golden flaxseed before breakfast decreases the 2 h postprandial glycemic response in men with T2DM.
餐后血糖波动与糖尿病的控制有关。长期食用亚麻籽可以降低血糖水平；然而，其对餐后血糖反应的影响尚不清楚。因此，本研究旨在评估男性 2 型糖尿病患者（T2DM）食用生亚麻籽对餐后 2 小时血糖曲线的急性影响。
这是一项随机交叉临床试验。19 名 T2DM 男性患者被随机分配到不服用（对照组）或服用 15 克磨碎生金亚麻籽（亚麻）的标准化早餐。分别在空腹和餐后 15、30、45、60、90 和 120 分钟测量血糖。评估了口感标志物（视觉吸引力、气味和味道的愉悦感）和味道强度（甜味、咸味、苦味、酸味和奶油味）。
在亚麻组中，血糖峰值上升和 2 小时 AUC 血糖反应分别降低了 17%（p=0.001）和 24%（p<0.001）。两组之间的血糖峰值时间、口感和口味参数没有差异。
早餐前摄入 15 克磨碎生金亚麻籽可降低 T2DM 男性的餐后 2 小时血糖反应。
