Bakdounes Anan, Akashe Nawal, Alchallah Mhd Obai, Alolabi Homam, Bakdounes Duaa, Mohsen Fatema, Darjazini Nahas Louei
Faculty of Medicine, Syrian Private University, Damascus, Syria.
Department of Surgery Division of Otorhinolaryngology, Faculty of Medicine, Syrian Private University, Damascus, Syria.
Ann Med Surg (Lond). 2022 Sep 2;81:104405. doi: 10.1016/j.amsu.2022.104405. eCollection 2022 Sep.
Ménière's Disease, a long-term debilitating disorder has been increasingly found among patients with hypothyroidism. Our study aims to evaluate the prevalence of ménière's disease among hypothyroid patients and assess the interrelationship between patients' symptomology and ménière's disease.
A cross-sectional study was performed at the endocrinology clinics at Damascus Hospital and Syrian Red Crescent Hospital, Damascus, Syria between September 2021 and January 2022. Patients with hypothyroidism were interviewed using a questionnaire. The questionnaire contained questions about socio-demographic information, hypothyroid history, diagnostic criteria of ménière's disease, chief complaint, medical history, and lab test results. Patients, who reported ménière's disease symptoms, were referred to the otorhinolaryngology clinic for confirmation or exclusion of ménière's disease. At the clinic, patients underwent an otoscopy and a pure tone audiometry, probable and definite ménière's disease was diagnosed accordingly.
Of 217 hypothyroid patients included in the sample, 17 (7.8%) were diagnosed with definite ménière's disease and 31 (14.3%) were diagnosed with probable ménière's disease. Hypothyroid symptoms reported among patients diagnosed with definite ménière's disease compared to no diagnosis differed by feeling low (χ2 (1, 217) = 4.014, p = 0.045), and depressive appearance (χ2 (1, 217) = 8.887, p = 0.003). Patients diagnosed with definite ménière's disease, probable ménière's disease, and both definite and probable ménière's disease were more likely to report that their symptoms affected their lifestyle compared to those that reported no effect (χ2 (3, 217) = 62.565, p < 0.001), (χ2 (3, 217) = 31.380, p < 0.001), and (χ2 (3, 217) = 35.542, p < 0.001), respectively.
A high number of hypothyroid patients were diagnosed with MD. Clinicians should consider clinically screening for MD among hypothyroid patients presenting to clinics.
梅尼埃病是一种长期使人衰弱的疾病，在甲状腺功能减退患者中越来越多地被发现。我们的研究旨在评估甲状腺功能减退患者中梅尼埃病的患病率，并评估患者症状与梅尼埃病之间的相互关系。
2021年9月至2022年1月期间，在叙利亚大马士革大马士革医院和叙利亚红新月会医院的内分泌科诊所进行了一项横断面研究。使用问卷对甲状腺功能减退患者进行访谈。问卷包含有关社会人口统计学信息、甲状腺功能减退病史、梅尼埃病诊断标准、主要症状、病史和实验室检查结果的问题。报告有梅尼埃病症状的患者被转诊至耳鼻喉科诊所，以确诊或排除梅尼埃病。在诊所，患者接受了耳镜检查和纯音听力测定，并据此诊断为可能的和明确的梅尼埃病。
在纳入样本的217例甲状腺功能减退患者中，17例（7.8%）被诊断为明确的梅尼埃病，31例（14.3%）被诊断为可能的梅尼埃病。与未诊断的患者相比，诊断为明确梅尼埃病的患者报告的甲状腺功能减退症状在情绪低落（χ2(1, 217) = 4.014，p = 0.045）和抑郁面容（χ2(1, 217) = 8.887，p = 0.003）方面存在差异。与报告症状无影响的患者相比，诊断为明确梅尼埃病、可能梅尼埃病以及明确和可能梅尼埃病的患者更有可能报告其症状影响了他们的生活方式（χ2(3, 217) = 62.565，p < 0.001）、（χ2(3, 217) = 31.380，p < 0.001）和（χ2(3, 217) = 35.542，p < 0.001）。
大量甲状腺功能减退患者被诊断为梅尼埃病。临床医生应考虑对到诊所就诊的甲状腺功能减退患者进行梅尼埃病的临床筛查。
