Patel J J, Levy D A, Nguyen S A, Rizk H G, Meyer T A
Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, USA.
Frank H Netter MD School of Medicine at Quinnipiac University, North Haven, Connecticut, USA.
J Laryngol Otol. 2020 Apr;134(4):293-301. doi: 10.1017/S002221512000081X.
Ménière's disease is a debilitating chronic peripheral vestibular disorder associated with psychiatric co-morbidities, notably depression.
Database searches were performed to identify studies that assessed depression in Ménière's disease. Metrics used to diagnose depression were extracted, along with the prevalence of depression in each study.
Fifteen studies from 8 different countries reported on 6587 patients. The weighted average age was 55.3 years (range, 21-88 years). Depression was measured by eight different scales, with Zung's Self-Rating Depression Scale used most often. A weighted proportion of 45.9 per cent of patients (confidence interval = 28.9-63.3) were depressed. Weighted averages (± standard deviations) of Beck's Depression Inventory and the Illness Behavior Questionnaire - Dysphoria were 8.5 ± 7.9 and 2.4 ± 1.7, respectively.
The prevalence of depression in patients with Ménière's disease is nearly 50 per cent. Treating otolaryngologists should have a low threshold to screen and refer appropriately. Identifying and treating depression should allow for improvement of overall quality of life in patients with Ménière's disease.
梅尼埃病是一种使人衰弱的慢性外周前庭疾病，与精神共病有关，尤其是抑郁症。
进行数据库检索，以识别评估梅尼埃病患者抑郁症的研究。提取用于诊断抑郁症的指标以及每项研究中抑郁症的患病率。
来自8个不同国家的15项研究报告了6587例患者。加权平均年龄为55.3岁（范围21 - 88岁）。使用8种不同量表测量抑郁症，其中最常使用的是zung氏自评抑郁量表。加权比例为45.9%的患者（置信区间 = 28.9 - 63.3）患有抑郁症。贝克抑郁量表和疾病行为问卷 - 烦躁不安的加权平均值（±标准差）分别为8.5±7.9和2.4±1.7。
梅尼埃病患者中抑郁症的患病率近50%。耳鼻喉科治疗医生应降低筛查门槛并进行适当转诊。识别和治疗抑郁症应有助于改善梅尼埃病患者的整体生活质量。
