Kasliwal Nimit, Yang Cheng, Martinez Eric J, Hebeler Robert F, Ramamoorthy Saravanan
Anesthesiology, Texas A&M College of Medicine, Dallas, USA.
Anesthesiology, Brooke Army Medical Center, San Antonio, USA.
Cureus. 2022 Aug 18;14(8):e28146. doi: 10.7759/cureus.28146. eCollection 2022 Aug.
Severe pulmonary hypertension and severe tricuspid regurgitation are often considered strict contraindications for orthotopic liver transplantation. A combined approach of tricuspid repair and subsequent liver transplantation could provide a novel approach for patients with severe pulmonary hypertension and tricuspid regurgitation to undergo orthotopic liver transplantation. A 62-year-old male with a history of end-stage renal disease on hemodialysis, cirrhosis, and third-degree atrioventricular heart block status post single lead pacemaker insertion presented for an orthotopic liver transplant. However, after placement of a Swan-Ganz catheter by the anesthesia team, the patient's central venous pressure was found to be high, and his mean pulmonary artery pressure was 40 mmHg. His case was canceled due to concern for poor postoperative outcomes after a subsequent transesophageal echocardiogram revealed a severely dilated right heart and 4+ tricuspid regurgitation with flow reversal into the hepatic veins. After discussion among the hospital's transplant committee, the patient was planned to have a tricuspid valve repair, liver transplant, and kidney transplant surgery several months later. The patient successfully underwent tricuspid valve repair and orthotopic liver transplant and then kidney transplant the following day.
重度肺动脉高压和重度三尖瓣反流通常被视为原位肝移植的严格禁忌证。三尖瓣修复并随后进行肝移植的联合方法可为患有重度肺动脉高压和三尖瓣反流的患者提供一种进行原位肝移植的新途径。一名62岁男性,有终末期肾病行血液透析、肝硬化病史,在植入单腔起搏器后出现三度房室传导阻滞,前来接受原位肝移植。然而,麻醉团队放置Swan-Ganz导管后,发现患者中心静脉压升高,平均肺动脉压为40 mmHg。随后经食管超声心动图显示右心严重扩张且三尖瓣反流4+伴血流逆向流入肝静脉,鉴于担心术后预后不佳,该患者的手术被取消。经医院移植委员会讨论后,计划数月后为该患者进行三尖瓣修复、肝移植和肾移植手术。患者成功接受了三尖瓣修复和原位肝移植,次日又接受了肾移植。