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肺结核后肺曲菌球与错构瘤并存:一例报告

Pulmonary aspergilloma coexisting with hamartoma in post pulmonary tuberculosis: A case report.

作者信息

Dewi Kristin Purnama, Dewi Ivana Purnama, Djatioetomo Yovita Citra Eka Dewi, Darwin Lyndon, Permatasari Ariani

机构信息

Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Airlangga University - Dr. Soetomo General Hospital, Surabaya, Indonesia.

Faculty of Medicine, Duta Wacana Christian University, Yogyakarta, Indonesia.

出版信息

Respir Med Case Rep. 2022 Sep 16;39:101738. doi: 10.1016/j.rmcr.2022.101738. eCollection 2022.

Abstract

INTRODUCTION

Aspergillosis is a fungal disease caused by the . Until now, the management of aspergilloma is still controversial, and there is no consensus among experts. Hamartoma is a benign tumor that can be found in the lung. We report a case of pulmonary aspergilloma coincidentally with hamartoma in pulmonary tuberculosis (TB) patients. Aspergilloma and hamartoma diagnoses are challenging because of various clinical symptoms.

CASE REPORT

A 46 years old man came to emergency unit with complaints shortness of breath, cough, and chest tightness. He also has a red-black blood streak and terrible odor sputum. He had a history of two episodes of pulmonary TB. Holistic physical and additional examinations were done. Patient was diagnosed with aspergillosis infection in post pulmonary TB. The patient was then undergoing surgery. From the pathology of lung tissue, we found hamartoma features. Antifungal, antibiotic, and supported therapy were given, and his condition improved after a month of hospitalization.

CONCLUSION

Pulmonary aspergilloma and hamartoma coincidence are rare diseases. Aspergilloma diagnosis is made based on clinical symptoms, radiological, and serological examination. Pulmonary hamartoma is generally asymptomatic. In this case, hamartoma was incidentally found in pathology examination. Prompt and precise diagnosis with good therapeutic management yield favorable outcomes.

摘要

引言

曲霉病是一种由……引起的真菌病。到目前为止,曲菌球的治疗仍存在争议,专家们尚未达成共识。错构瘤是一种可在肺部发现的良性肿瘤。我们报告一例肺结核患者同时合并肺曲菌球和错构瘤的病例。由于各种临床症状,曲菌球和错构瘤的诊断具有挑战性。

病例报告

一名46岁男性因呼吸急促、咳嗽和胸闷前来急诊。他还有红黑色血丝痰和恶臭痰液。他有两次肺结核病史。进行了全面的体格检查和其他检查。患者被诊断为肺结核后曲霉菌感染。然后该患者接受了手术。从肺组织病理学检查中,我们发现了错构瘤特征。给予了抗真菌、抗生素及支持治疗,住院一个月后他的病情有所改善。

结论

肺曲菌球和错构瘤同时存在是罕见疾病。曲菌球的诊断基于临床症状、影像学和血清学检查。肺错构瘤通常无症状。在本病例中,错构瘤是在病理检查中偶然发现的。及时、准确的诊断并进行良好的治疗管理可产生良好的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b567/9508335/af5b75152083/gr1.jpg

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