Centre for Data and Knowledge Integration for Health (CIDACS), Oswaldo Cruz Foundation, Salvador, Brazil.
Departments of Infectious Disease Epidemiology (JMP) and Epidemiology and Population Health (LS), Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Int J Epidemiol. 2022 Dec 13;51(6):1847-1861. doi: 10.1093/ije/dyac188.
Cardiovascular disease (CVD) has a disproportionate effect on mortality among the poorest people. We assessed the impact on CVD and all-cause mortality of the world's largest conditional cash transfer, Brazil's Bolsa Família Programme (BFP).
We linked administrative data from the 100 Million Brazilian Cohort with BFP receipt and national mortality data. We followed individuals who applied for BFP between 1 January 2011 and 31 December 2015, until 31 December 2015. We used marginal structural models to estimate the effect of BFP on all-age and premature (30-69 years) CVD and all-cause mortality. We conducted stratified analyses by levels of material deprivation and access to healthcare. We checked the robustness of our findings by restricting the analysis to municipalities with better mortality data and by using alternative statistical methods.
We studied 17 981 582 individuals, of whom 4 855 324 were aged 30-69 years. Three-quarters (76.2%) received BFP, with a mean follow-up post-award of 2.6 years. We detected 106 807 deaths by all causes, of which 60 893 were premature; and 23 389 CVD deaths, of which 15 292 were premature. BFP was associated with reductions in premature all-cause mortality [hazard ratio (HR) = 0.96, 95% CI = 0.94-0.98], premature CVD (HR = 0.96, 95% CI = 0.92-1.00) and all-age CVD (HR = 0.96, 95% CI = 0.93-1.00) but not all-age all-cause mortality (HR = 1.00, 95% CI = 0.98-1.02). In stratified and robustness analyses, BFP was consistently associated with mortality reductions for individuals living in the two most deprived quintiles.
BFP appears to have a small to null effect on premature CVD and all-cause mortality in the short term; the long-term impact remains unknown.
心血管疾病(CVD)对最贫困人口的死亡率有不成比例的影响。我们评估了世界上最大的有条件现金转移,巴西家庭福利计划(BFP)对 CVD 和全因死亡率的影响。
我们将巴西 1 亿人队列的行政数据与 BFP 接受情况和国家死亡率数据相联系。我们对 2011 年 1 月 1 日至 2015 年 12 月 31 日期间申请 BFP 的个人进行了随访,直到 2015 年 12 月 31 日。我们使用边缘结构模型来估计 BFP 对全年龄段和早发性(30-69 岁)CVD 和全因死亡率的影响。我们按物质剥夺程度和获得医疗保健的机会进行分层分析。我们通过将分析仅限于死亡率数据较好的城市和使用替代统计方法来检查我们研究结果的稳健性。
我们研究了 17981582 人,其中 4855324 人年龄在 30-69 岁之间。四分之三(76.2%)的人接受了 BFP,平均随访期为获奖后 2.6 年。我们检测到了 106807 例全因死亡,其中 60893 例是早发性死亡;23389 例 CVD 死亡,其中 15292 例是早发性死亡。BFP 与早发性全因死亡率降低相关[风险比(HR)=0.96,95%可信区间(CI)=0.94-0.98]、早发性 CVD(HR=0.96,95%CI=0.92-1.00)和全年龄段 CVD(HR=0.96,95%CI=0.93-1.00),但与全年龄段全因死亡率无关(HR=1.00,95%CI=0.98-1.02)。在分层和稳健性分析中,BFP 与生活在最贫困两个五分位数的个体的死亡率降低相关。
BFP 似乎对短期早发性 CVD 和全因死亡率有较小或无影响;长期影响尚不清楚。