Pellettieri L, Sjölander U, Jakobsson K E
Acta Neurochir (Wien). 1987;86(1-2):6-11. doi: 10.1007/BF01419497.
This is a retrospective study of 134 patients operated on for solitary brain metastasis at the University Hospital in Uppsala, Sweden between 1963 and 1982. All the patients underwent postoperative radiation therapy. A statistical evaluation of different prognostic factors was made in order to create a prognostic model, a so-called risk profile, to be used for future patients. The most important factors for the making of risk profiles were found to be the "histological diagnosis" followed by the "location" in the brain, then the "state on admission" and the "age" at admission in that declining order. All these variables separately and together, i.e., as risk profiles, were matched against the outcome during survival as Karnofsky's scores and against the length of survival time. The results are shown in a diagram giving the surgeon grounds for his decision-making for or against operation and also for pre-operative information.
这是一项对1963年至1982年间在瑞典乌普萨拉大学医院接受孤立性脑转移瘤手术的134例患者的回顾性研究。所有患者均接受了术后放射治疗。为了创建一个预后模型，即所谓的风险概况，用于未来的患者，对不同的预后因素进行了统计评估。发现用于制定风险概况的最重要因素依次为“组织学诊断”、脑内“位置”、“入院时状态”和入院时“年龄”。所有这些变量单独以及一起，即作为风险概况，与生存期间的结果（以卡诺夫斯基评分表示）以及生存时间长度进行了匹配。结果以图表形式呈现，为外科医生决定是否进行手术以及术前提供信息提供了依据。
