Department of Pediatrics, College of Medicine, University of Karbala, Karbala, Iraq.
J Med Life. 2022 Aug;15(8):994-999. doi: 10.25122/jml-2022-0073.
This study aimed to determine the morbidity and mortality patterns among infants of diabetic mothers admitted to the neonatal care unit in Karbala pediatric teaching hospital. The study enrolled fifty diabetic infants (pregestational and gestational) admitted to the ward from the 1 of October 2013 to the 30 of January 2014. Data on delivery mode, gestational age, birth weight, other associated morbidities, investigation results, therapy, length of hospital stay, and outcome were collected and compared to infants of non-diabetic mothers admitted during the same period. A retrospective analysis of maternal data was performed. 62% of infants were born to mothers with gestational diabetes, and 38% were born to mothers with pre-gestational diabetes. 86% were born by caesarian section, of which 35% were by emergency cesarean section. The mean gestational age of infants of diabetic mothers was 37w1d±1.88, and 29 (64%) had macrosomia. The most typical morbidities were hypoglycemia (significantly higher in infants of diabetic mothers (IDMs) than infants of non-diabetic mothers) and hyperbilirubinemia in 36 (72%) and 24 (48%), respectively. There was no difference in morbidity patterns between infants of pregestational and gestational diabetic mothers except for macrosomia, and transient tachypnea of newborns was higher in gestational diabetes. The mortality rate was not significantly higher in IDMs. Diabetes during pregnancy has a serious effect on neonates and their mothers. The commenced morbidities in IDMs were hypoglycemia, macrosomia, and hyperbilirubinemia, so strict control of blood glucose level during pregnancy and education of diabetic women is essential before and during gestation.
本研究旨在确定在卡尔巴拉儿科教学医院新生儿护理病房住院的糖尿病母亲所生婴儿的发病率和死亡率模式。本研究纳入了 2013 年 10 月 1 日至 2014 年 1 月 30 日期间入住该病房的 50 名糖尿病婴儿（孕前和妊娠期）。收集了分娩方式、胎龄、出生体重、其他相关合并症、检查结果、治疗、住院时间和结局等数据，并与同期住院的非糖尿病母亲所生婴儿进行了比较。对母亲的数据进行了回顾性分析。62%的婴儿是由患有妊娠期糖尿病的母亲所生，38%的婴儿是由患有孕前糖尿病的母亲所生。86%的婴儿是通过剖宫产分娩的，其中 35%是急诊剖宫产。糖尿病母亲所生婴儿的平均胎龄为 37w1d±1.88，29 例（64%）为巨大儿。最典型的合并症是低血糖（糖尿病母亲所生婴儿（IDM）显著高于非糖尿病母亲所生婴儿）和高胆红素血症，分别为 36 例（72%）和 24 例（48%）。除了巨大儿之外，孕前和妊娠期糖尿病母亲所生婴儿的发病模式没有差异，妊娠期糖尿病的新生儿暂时性呼吸急促发生率更高。IDM 的死亡率没有显著升高。妊娠期间的糖尿病对新生儿及其母亲有严重影响。IDM 开始出现的并发症是低血糖、巨大儿和高胆红素血症，因此在妊娠前和妊娠期间，必须严格控制血糖水平，并对糖尿病妇女进行教育。
