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使用NeuroShell分析与血培养阳性相关的患者参数:一项回顾性病历审查

Patient Parameters Associated With a Positive Blood Culture Using NeuroShell: A Retrospective Chart Review.

作者信息

Giovane Richard, Sheppard Robert A

机构信息

Family Medicine, University of Alabama at Birmingham, Tuscaloosa, USA.

Internal Medicine, University of Alabama at Birmingham, Tuscaloosa, USA.

出版信息

Cureus. 2022 Aug 31;14(8):e28635. doi: 10.7759/cureus.28635. eCollection 2022 Aug.

DOI:10.7759/cureus.28635
PMID:36196317
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9524715/
Abstract

Bacteremia is a common and life-threatening condition. It has an incidence of 140 to 160 per 100,000 person-years in the United States. Since bacteremia has many presentations, it can be challenging to diagnose. Subsequently there are very few guidelines on when to order a blood culture in an emergency setting. Neural networks are a means of machine learning and are presently being used in medicine to aid in decision making. With the use of machine learning, 22 variables that have been associated with infection and bacteremia were used to build a neural network to determine which variables associated with bacteremia are most associated with a positive blood culture.

摘要

菌血症是一种常见且危及生命的病症。在美国,其发病率为每10万人年140至160例。由于菌血症有多种表现形式,诊断可能具有挑战性。随后,关于在紧急情况下何时进行血培养的指南非常少。神经网络是机器学习的一种手段,目前正在医学中用于辅助决策。通过使用机器学习,22个与感染和菌血症相关的变量被用于构建一个神经网络,以确定哪些与菌血症相关的变量与血培养阳性最相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c844/9524715/3f59224b973b/cureus-0014-00000028635-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c844/9524715/3f59224b973b/cureus-0014-00000028635-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c844/9524715/3f59224b973b/cureus-0014-00000028635-i01.jpg

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本文引用的文献

1
Does This Patient Need Blood Cultures? A Scoping Review of Indications for Blood Cultures in Adult Nonneutropenic Inpatients.是否需要给这位患者做血培养?成人非中性粒细胞减少住院患者血培养适应证的范围评价。
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Practical Guidance for Clinical Microbiology Laboratories: A Comprehensive Update on the Problem of Blood Culture Contamination and a Discussion of Methods for Addressing the Problem.临床微生物学实验室实用指南:血液培养污染问题的全面更新及解决方法讨论。
Clin Microbiol Rev. 2019 Oct 30;33(1). doi: 10.1128/CMR.00009-19. Print 2019 Dec 18.
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Cellulitis: A Review.
蜂窝织炎:综述。
JAMA. 2016 Jul 19;316(3):325-37. doi: 10.1001/jama.2016.8825.
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Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).制定脓毒性休克的新定义并评估新的临床标准:用于第三次脓毒症和脓毒性休克国际共识定义(Sepsis-3)。
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Multidisciplinary team review of best practices for collection and handling of blood cultures to determine effective interventions for increasing the yield of true-positive bacteremias, reducing contamination, and eliminating false-positive central line-associated bloodstream infections.多学科团队对血培养采集和处理的最佳实践进行审查,以确定有效的干预措施,提高真阳性菌血症的检出率,减少污染,并消除与中心静脉导管相关的血流感染的假阳性。
Am J Infect Control. 2015 Nov;43(11):1222-37. doi: 10.1016/j.ajic.2015.06.030. Epub 2015 Aug 19.
7
Prediction of bacteremia in the emergency department: an external validation of a clinical decision rule.急诊科中菌血症的预测:一项临床决策规则的外部验证
Eur J Emerg Med. 2016 Feb;23(1):44-9. doi: 10.1097/MEJ.0000000000000203.
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Multistate point-prevalence survey of health care-associated infections.多州医疗机构相关性感染的时点患病率调查。
N Engl J Med. 2014 Mar 27;370(13):1198-208. doi: 10.1056/NEJMoa1306801.
9
Does this adult patient with suspected bacteremia require blood cultures?这位疑似菌血症的成年患者需要进行血培养吗?
JAMA. 2012 Aug 1;308(5):502-11. doi: 10.1001/jama.2012.8262.
10
Inadequacy of temperature and white blood cell count in predicting bacteremia in patients with suspected infection.体温和白细胞计数在预测疑似感染患者菌血症方面的不足。
J Emerg Med. 2012 Mar;42(3):254-9. doi: 10.1016/j.jemermed.2010.05.038. Epub 2010 Jul 31.