登革热的临床表现和血小板特征：一项回顾性研究。
Clinical Presentation and Platelet Profile of Dengue Fever: A Retrospective Study.
作者信息
Vijay J, Anuradha N, Anbalagan Viknesh P
机构信息
Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, IND.
出版信息
Cureus. 2022 Aug 31;14(8):e28626. doi: 10.7759/cureus.28626. eCollection 2022 Aug.
BACKGROUND
Dengue fever (DF) is a mosquito-borne viral illness carried worldwide by and mosquitoes. The aim of the present study was to observe the different clinical presentations of dengue fever and the platelet profile analysis in DF patients.
METHODS
This retrospective study was performed on 130 diagnosed patients with dengue fever, aged over 14 years. Data collection included patient age, gender, clinical manifestations, hematocrit, platelet count, and evidence of plasma leakage.
RESULTS
Most of the patients belong to the 21-30 year age group, with a greater number of males compared to females. The common presentation of dengue fever was fever and myalgia, observed in 100% and 95.3% of the patients, respectively. A platelet count of less than 1,00,000 was observed in 77% of patients, whereas decreased total leukocyte count (TLC) and hematocrit were observed in 52.3% and 40% of patients, respectively. About 46.15% of patients had bradycardia on examination. Pleural effusion and ascites were found in 20.7% and 15.3% of patients, respectively.
CONCLUSION
Patients presenting with fever, hemorrhagic symptoms, or signs of plasma leakage should be promptly suspected, timely diagnosed and managed on the grounds of dengue fever.
背景
登革热是一种由伊蚊和白纹伊蚊传播的全球性蚊媒病毒性疾病。本研究的目的是观察登革热患者不同的临床表现及血小板特征分析。
方法
本回顾性研究对130例年龄超过14岁的确诊登革热患者进行。数据收集包括患者年龄、性别、临床表现、血细胞比容、血小板计数及血浆渗漏证据。
结果
大多数患者属于21 - 30岁年龄组，男性数量多于女性。登革热的常见表现为发热和肌痛，分别在100%和95.3%的患者中观察到。77%的患者血小板计数低于100,000，而分别有52.3%和40%的患者白细胞总数（TLC）和血细胞比容降低。约46.15%的患者检查时出现心动过缓。分别有20.7%和15.3%的患者发现胸腔积液和腹水。
结论
出现发热、出血症状或血浆渗漏迹象的患者应立即怀疑，并根据登革热及时诊断和处理。
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