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代谢组学——家畜研究的有力工具。

Metabolomics-a powerful tool in livestock research.

机构信息

Southern Regional Station, ICAR-National Dairy Research Institute, Bangalore, India.

Animal Genetics and Breeding Division, Hassan Veterinary College, Hassan, India.

出版信息

Anim Biotechnol. 2023 Dec;34(7):3237-3249. doi: 10.1080/10495398.2022.2128814. Epub 2022 Oct 6.

Abstract

Advancements in the Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) along with recent developments in omics sciences have resulted in a better understanding of molecular mechanisms and pathways associated with the physio-pathological state of the animal. Metabolomics is a post-genomics tool that deals with small molecular metabolites in a given set of time which provides clear information about the status of an organism. Recently many researchers mainly focus their research on metabolomics studies due to its valuable information in the various fields of livestock management and precision dairying. The main aim of the present review is to provide an insight into the current research output from different sources and application of metabolomics in various areas of livestock including nutri-metabolomics, disease diagnosis advancements, reproductive disorders, pharmaco-metabolomics, genomics studies, and dairy production studies. The present review would be helpful in understanding the metabolomics methodologies and use of livestock metabolomics in various areas in a brief way.

摘要

随着核磁共振(NMR)和质谱(MS)的进步以及组学科学的最新发展,人们对与动物生理病理状态相关的分子机制和途径有了更好的理解。代谢组学是一种后基因组学工具,它研究给定时间内的小分子代谢物,提供有关生物体状态的明确信息。最近,由于其在畜牧业管理和精准奶牛养殖等各个领域的宝贵信息,许多研究人员主要专注于代谢组学研究。本综述的主要目的是提供对不同来源的当前研究成果的深入了解,并介绍代谢组学在畜牧业各个领域的应用,包括营养代谢组学、疾病诊断进展、生殖障碍、药物代谢组学、基因组学研究和奶牛生产研究。本综述将有助于以简要的方式了解代谢组学方法以及在各个领域中应用于家畜的代谢组学。

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