Du Chenyuan, Chen Jiayue, Ma Xiaoyan, Tu Wenzhen, Chen Langlang, Liu Jian, Zhou Dan, Chen Xinying, Zhang Jiulong, Tian Hongjun, Zhuo Chuanjun, Jiang Deguo
Department of Psychiatry, Wenzhou Seventh Peoples Hospital, Wenzhou, China.
Department of Psychiatry, Nankai University Affiliated Tianjin Fourth Center Hospital, Tianjin Fourth Center Hospital, Tianjin, China.
Front Psychiatry. 2022 Sep 20;13:992745. doi: 10.3389/fpsyt.2022.992745. eCollection 2022.
Accurate assessment of anxiety disorders and their symptomatology in schizophrenic patients is important for prognosis and treatment. Measuring anxiety on the traditional anxiety assessment scales such as the Hamilton Anxiety Rating (HAMA) Scale or the self-rating depression scale (SAS) is challenging and often considered unsuitable for assessing anxiety symptoms in patients with schizophrenia. The Staden schizophrenia anxiety rating scale (S-SARS) has been shown to reliably measure specified and undifferentiated anxiety in schizophrenia. The present study aims to test the reliability and validity of the S-SARS version, thereby facilitating Chinese psychiatrists in assessing anxiety symptoms in schizophrenic patients. A total of 300 patients meeting ICD-10 diagnostic criteria of schizophrenia were recruited by convenience sampling. We used the exploratory factor analysis (EFA) to evaluate the structural validity of S-SARS and receiver operating characteristic (ROC) curves to acquire the cutoff point of S-SARS to define the severity of anxiety. Internal consistency was assessed using Cronbach's and Krippendorff's α scores. 1-week test-retest reliability was assessed using the intra-class correlation coefficient (ICC). Correlation analysis with HAMA was used to determine the Chinese version of S-SARS criterion validity. We have the following results: Our version of S-SARS showed Cronbach's α score as 0.899, Krippendorff's α as 0.874, and a correlation coefficient of 0.852 between S-SARS and HAMA. The EPA demonstrated that the contribution rate of major factors was 69.45%. All the items of S-SARS were located in one factor and showed a high factor load (0.415-0.837). The correlation coefficient of S-SARS and HAMA was 0.852. Our results indicated that Chinese version of S-SARS showed good constructive validity and reliability. It also showed better criterion validity compared to HAMA. The S-SARS and its Chinese version can thus serve as an effective tool for assessing anxiety symptoms in patients with schizophrenia.
准确评估精神分裂症患者的焦虑症及其症状表现对预后和治疗至关重要。使用传统焦虑评估量表（如汉密尔顿焦虑量表（HAMA）或自评抑郁量表（SAS））来测量焦虑具有挑战性，且通常被认为不适用于评估精神分裂症患者的焦虑症状。斯塔登精神分裂症焦虑评定量表（S-SARS）已被证明能够可靠地测量精神分裂症中特定的和未分化的焦虑。本研究旨在测试S-SARS版本的信度和效度，从而帮助中国精神科医生评估精神分裂症患者的焦虑症状。通过便利抽样招募了300名符合ICD-10精神分裂症诊断标准的患者。我们使用探索性因素分析（EFA）来评估S-SARS的结构效度，并使用受试者工作特征（ROC）曲线来获取S-SARS的截断点以定义焦虑的严重程度。使用克朗巴赫系数和克里彭多夫系数α分数评估内部一致性。使用组内相关系数（ICC）评估1周重测信度。与HAMA进行相关分析以确定中文版S-SARS的效标效度。我们有以下结果：我们版本的S-SARS的克朗巴赫系数α分数为0.899，克里彭多夫系数α为0.874，S-SARS与HAMA之间的相关系数为0.852。探索性因素分析表明主要因素的贡献率为69.45%。S-SARS的所有项目都位于一个因素中，并显示出较高的因素负荷（0.415 - 0.837）。S-SARS与HAMA的相关系数为0.852。我们的结果表明中文版S-SARS具有良好的结构效度和信度。与HAMA相比，它还显示出更好的效标效度。因此，S-SARS及其中文版可作为评估精神分裂症患者焦虑症状的有效工具。
