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短期脊髓刺激是治疗疱疹相关性神经痛的有效方法——中国全国专家共识

Short-term spinal cord stimulation is an effective therapeutic approach for herpetic-related neuralgia-A Chinese nationwide expert consensus.

作者信息

Sun Wuping, Jin Yi, Liu Hongjun, Yang Dong, Sun Tao, Wang Yaping, Fan Yinghui, Fan Xiaochong, Jin Xiaohong, Wan Li, Gu Ke, Feng Zhiying, Liu Yiming, Mao Peng, Song Tao, Dequan Wang, Xiong Donglin, Luan Guoming, Wang Xiaoping, Fan Bifa, Xiao Lizu

机构信息

Department of Pain Medicine and Shenzhen Municipal Key Laboratory for Pain Medicine, Shenzhen Nanshan People's Hospital and the 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China.

Department of Pain Management, Jinling Hospital, Nanjing, China.

出版信息

Front Aging Neurosci. 2022 Sep 20;14:939432. doi: 10.3389/fnagi.2022.939432. eCollection 2022.

Abstract

PURPOSE

Short-term spinal cord stimulation (st-SCS) has been widely used to treat herpetic-related neuralgia (HN) in China for several years, but is still heavily debated as it has no strong evidence in clinical application. Therefore, a questionnaire survey among the Chinese pain specialist workgroup of the Chinese Neuromodulation Society and Chinese Medical Doctor Association was carried out to achieve a consensus about the clinical use of st-SCS for HN treatment.

METHODS

The contents of the questionnaire include basic information about doctors (hospital level, work experience, training, procedure numbers, etc.), efficacy, indications, and contraindications of st-SCS, operation conditions, and preoperative preparation of st-SCS, and the prospect of the st-SCS procedure. Initially, the survey was conducted on 110 experts who have practiced the st-SCS procedure from all over the provinces in China. Finally, valuable data was calculated from the 110 questionnaires excluding the doctors with <1 year of experience of st-SCS, <10 cases of procedures per year, and no standard training in SCS technique.

RESULTS

Based on the 110 questionnaires, it is estimated that 5,000 to 10,000 cases of electrical stimulation are carried out nationwide each year. Sixty-nine valid questionnaires acquired from senior pain physicians were more valuable and specialized in the efficacy, indications, and contraindications of st-SCS for HN. It was commonly agreed (97.10%) that the HN patients with <3 months will obtain good effectiveness (patient satisfaction rate ≥50%). Almost all (98.55%) agreed that st-SCS can be used in SHN patients, there was a common agreement (72.46%) that AHN patients are an indication of st-SCS, and more than half agreement (53.62%) that st-SCS may be fit for early PHN (3-6 months). A common agreement (79.71%) was achieved that more than half of HN patients had the experience of nerve block or nerve pulsed RF. A similarly large number of experts 57/69 (82.61%) agreed that an 80% paresthesia coverage should be achieved at the test stimulation and 57/69 (82.61%) agreed that the treatment of st-SCS need be persistent for 1-2 weeks.

CONCLUSIONS

Early HN patients can get an effective outcome from the treatment of st-SCS and maybe the indication of st-SCS. Moreover, standardized training for pain physicians and basic research and clinical studies are warranted.

摘要

目的

短期脊髓刺激(st-SCS)在中国已广泛应用于治疗疱疹相关性神经痛(HN)数年,但由于临床应用中缺乏有力证据,仍存在激烈争论。因此,对中国神经调控学会和中国医师协会的中国疼痛专科医生工作小组进行了问卷调查,以就st-SCS治疗HN的临床应用达成共识。

方法

问卷内容包括医生的基本信息(医院级别、工作经验、培训、手术例数等)、st-SCS的疗效、适应证和禁忌证、手术条件、st-SCS的术前准备以及st-SCS手术的前景。最初,对来自中国各省的110名实施过st-SCS手术的专家进行了调查。最后,从110份问卷中计算出有价值的数据,排除了st-SCS经验不足1年、每年手术例数少于10例且未接受过SCS技术标准培训的医生。

结果

根据110份问卷估计,全国每年进行5000至10000例电刺激治疗。从资深疼痛科医生那里获得的69份有效问卷更有价值,专门针对st-SCS治疗HN的疗效、适应证和禁忌证。普遍认为(97.10%)病程小于3个月的HN患者能获得良好疗效(患者满意率≥50%)。几乎所有(98.55%)人都同意st-SCS可用于带状疱疹后神经痛(PHN)患者,普遍认为(72.46%)急性带状疱疹性神经痛(AHN)患者是st-SCS的适应证,超过半数(53.62%)人认为st-SCS可能适用于早期PHN(3 - 6个月)。普遍达成共识(79.71%),超过半数的HN患者有过神经阻滞或神经脉冲射频的经历。同样有大量专家57/69(82.61%)同意在测试刺激时应达到80%的感觉异常覆盖范围,57/69(82.61%)同意st-SCS治疗需持续1 - 2周。

结论

早期HN患者可从st-SCS治疗中获得有效结果,可能是st-SCS的适应证。此外,疼痛科医生的标准化培训以及基础研究和临床研究是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95e1/9530637/c486d5a8cce7/fnagi-14-939432-g0001.jpg

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