Zhang Siwei, Yang Kang, Wang Bin
Department of Ophthalmology, Hefei Bright Eye Hospital, Hefei 230001, Anhui, China.
Department of Ophthalmology, Fuyang Women and Children's Hospital, Fuyang 236000, Anhui, China.
Evid Based Complement Alternat Med. 2022 Sep 28;2022:5075447. doi: 10.1155/2022/5075447. eCollection 2022.
To evaluate the effect of the VFQ-25 scale on the efficacy of Nd : YAG laser ablation in patients with different severity of vitreous opacities.
From January 2020 to March 2021, data of patients who presented to our department and were diagnosed with vitreous opacity were collected, and the severity of vitreous opacity was divided into four grades: I, II, III, and IV. Preoperative visual acuity, intraocular pressure, dilated fundus, B ultrasound, and other examinations were performed, and the patients were scored using the VFQ-25 scale. All patients underwent Nd : YAG laser ablation and were followed for 6 months. The VFQ-25 scale was again used postoperatively to score the patient's efficacy. The general information and clinical characteristics of the patients we collected. The Spearman's test was used to evaluate the correlation between VFQ-25 score and Nd : YAG laser efficacy in patients.
A total of 80 patients (95 eyes) were included in this study. Vitreous opacities were grade I in 56 eyes (58.9%), grade II in 22 eyes (23.2%), grade III in 10 eyes (10.5%), and grade IV in 7 eyes (7.4%). Compared with preoperative scores, patients with vitreous opacity had significantly higher postoperative scores in terms of overall health (36.54 ± 17.06 vs 33.52 ± 16.74), overall visual acuity (60.39 ± 14.24 vs 57.56 ± 13.13), color vision (88.94 ± 12.56 vs 86.38 ± 12.37), and peripheral visual acuity (74.06 ± 18.38 vs 72.20 ± 18.79) items (all < 0.001). The overall response rates of vitreous opacities I, II, III, and IV were 100%, 90.9%, 80.0%, and 71.4%, respectively. There was a significant correlation between the postoperative VFQ-25 total score, and the therapeutic effect of laser ablation for grade I vitreous opacities, with a correlation coefficient of 0.417 (=0.001). The correlation coefficient between the total score of postoperative VFQ-25 and the treatment effect of grade II vitreous opacity was 0.622 (=0.002). However, the correlation between the postoperative efficacy of grade III and IV patients and the VFQ-25 score was not significant.
In patients with different degrees of vitreous opacity undergoing Nd : YAG laser vitreous ablation, the overall health, overall visual acuity, color vision, and peripheral visual acuity were improved after surgery, and the VFQ-25 score was significantly correlated with the postoperative efficacy, which is worthy of clinical use.
评估VFQ - 25量表对不同严重程度玻璃体混浊患者Nd : YAG激光消融疗效的影响。
收集2020年1月至2021年3月来我院就诊并被诊断为玻璃体混浊患者的数据，将玻璃体混浊严重程度分为I、II、III、IV四级。进行术前视力、眼压、散瞳眼底、B超等检查，并采用VFQ - 25量表对患者进行评分。所有患者均接受Nd : YAG激光消融治疗，并随访6个月。术后再次使用VFQ - 25量表对患者疗效进行评分。收集患者的一般资料和临床特征。采用Spearman检验评估患者VFQ - 25评分与Nd : YAG激光疗效之间的相关性。
本研究共纳入80例患者（95只眼）。其中I级玻璃体混浊56只眼（58.9%），II级22只眼（23.2%），III级10只眼（10.5%），IV级7只眼（7.4%）。与术前评分相比，玻璃体混浊患者术后在总体健康（36.54 ± 17.06 vs 33.52 ± 16.74）、总体视力（60.39 ± 14.24 vs 57.56 ± 13.13）、色觉（88.94 ± 12.56 vs 86.38 ± 12.37）和周边视力（74.06 ± 18.38 vs 72.20 ± 18.79）项目上的评分均显著提高（均P < 0.001）。I、II、III、IV级玻璃体混浊的总体有效率分别为100%、90.9%、80.0%和 71.4%。术后VFQ - 25总分与I级玻璃体混浊激光消融治疗效果之间存在显著相关性，相关系数为0.417（P = 0.001）。术后VFQ - 25总分与II级玻璃体混浊治疗效果之间的相关系数为0.622（P = 0.002）。然而，III级和IV级患者术后疗效与VFQ - 25评分之间的相关性不显著。
不同程度玻璃体混浊患者接受Nd : YAG激光玻璃体消融术后，总体健康、总体视力、色觉和周边视力均得到改善，且VFQ - 25评分与术后疗效显著相关，值得临床应用。
