约旦2型糖尿病患者血脂异常的患病率、模式及其相关因素：一项横断面研究
Prevalence and Pattern of Dyslipidemia and Its Associated Factors Among Patients with Type 2 Diabetes Mellitus in Jordan: A Cross-Sectional Study.
作者信息
Al Quran Thekraiat M, Bataineh Ziad A, Al-Mistarehi Abdel-Hameed, Zein Alaabdin Anas M, Allan Hadeel, Al Qura'an Anood, Weshah Shatha M, Alanazi Anfal A, Khader Yousef S
机构信息
Department of Public Health and Family Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Department of General Surgery, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
出版信息
Int J Gen Med. 2022 Oct 4;15:7669-7683. doi: 10.2147/IJGM.S377463. eCollection 2022.
BACKGROUND
Dyslipidemia and type 2 diabetes mellitus (T2DM) are growing health problems, particularly in developing countries. This study aimed to determine the prevalence and pattern of dyslipidemia and its associated factors among patients with T2DM.
METHODS
A cross-sectional study was conducted among patients with T2DM attending Family Medicine Clinics in Jordan between August 2017 and March 2019. The socio-demographics, clinical features, medications, and laboratory findings were collected. These laboratory findings included high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglycerides (TGs).
RESULTS
A total of 870 patients with T2DM were included. The prevalence of dyslipidemia among patients with T2DM was 91.4%. The most common patterns of dyslipidemia were low HDL-C (66.2%), high LDL-C (62.1%), and hypertriglyceridemia (58.2%). Female gender, obesity, and hypertension were associated with diabetic dyslipidemia patterns. T2DM duration and poor glycemic control were associated with high LDL-C and hypercholesterolemia. Hypertriglyceridemia was associated with poor glycemic control and smoking.
CONCLUSION
Dyslipidemia is highly prevalent among patients with T2DM. Evidence -based interventions are needed to prevent and control dyslipidemia among patients with T2DM in Jordan.
背景
血脂异常和2型糖尿病（T2DM）是日益严重的健康问题，在发展中国家尤为如此。本研究旨在确定T2DM患者中血脂异常的患病率、模式及其相关因素。
方法
2017年8月至2019年3月期间，对约旦家庭医学诊所的T2DM患者进行了一项横断面研究。收集了社会人口统计学、临床特征、用药情况和实验室检查结果。这些实验室检查结果包括高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）、总胆固醇（TC）和甘油三酯（TGs）。
结果
共纳入870例T2DM患者。T2DM患者中血脂异常的患病率为91.4%。最常见的血脂异常模式为HDL-C降低（66.2%）、LDL-C升高（62.1%）和高甘油三酯血症（58.2%）。女性、肥胖和高血压与糖尿病血脂异常模式相关。T2DM病程和血糖控制不佳与LDL-C升高和高胆固醇血症相关。高甘油三酯血症与血糖控制不佳和吸烟相关。
结论
血脂异常在T2DM患者中非常普遍。需要采取循证干预措施来预防和控制约旦T2DM患者的血脂异常。
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