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性别差异对健康保护行为的影响及其对台湾 COVID-19 大流行的启示:一项基于人群的研究。

Gender differences in health protective behaviours and its implications for COVID-19 pandemic in Taiwan: a population-based study.

机构信息

School of Medicine, National Taiwan University, Taipei, Taiwan.

Department of Sociology, National Taiwan University, Taipei, Taiwan.

出版信息

BMC Public Health. 2022 Oct 12;22(1):1900. doi: 10.1186/s12889-022-14288-1.

Abstract

INTRODUCTION

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection produces more severe symptoms and a higher mortality in men than in women. The role of biological sex in the immune response to SARS-CoV-2 is believed to explain this sex disparity. However, the contribution of gender factors that influence health protective behaviors and therefore health outcomes, remains poorly explored.

METHODS

We assessed the contributions of gender in attitudes towards the COVID-19 pandemic, using a hypothetical influenza pandemic data from the 2019 Taiwan Social Change Survey. Participants were selected through a stratified, three-stage probability proportional-to-size sampling from across the nation, to fill in questionnaires that asked about their perception of the hypothetical pandemic, and intention to adopt health protective behaviors.

RESULTS

A total of 1,990 participants (median age = 45·92 years, 49% were women) were included. Significant gender disparities (p < .001) were observed. The risk perception of pandemic (OR = 1·28, 95% CI [1·21 - 1·35], p < .001), older age (OR = 1·06, 95% CI [1·05 - 1·07], p < .001), female gender (OR = 1·18, 95% CI [1·09-1·27], p < .001), higher education (OR = 1·10, 95% CI [1·06 - 1·13], p < .001), and larger family size (OR = 1·09, 95% CI [1·06 - 1·15], p < .001) were positively associated with health protective behaviors. The risk perception of pandemic (OR = 1·25, 95% CI [1·15 - 1·36]), higher education (OR = 1·07, 95% CI [1·02 - 1·13], p < .05), being married (OR = 1·17, 95% CI [1·01-1·36, p < .05), and larger family size (OR = 1·33, 95% CI [1·25 - 1·42], p < .001), were positively associated with intention to receive a vaccine. However, female gender was negatively associated with intention to receive a vaccine (OR = 0·85, 95% CI [0·75 - 0·90], p < ·01) and to comply with contact-tracing (OR = 0·95, 95% CI [0·90 - 1·00], p < .05) compared to men. Living with children was also negatively associated with intention to receive vaccines (OR = 0·77, 95% CI [0·66 - 0·90], p < .001).

CONCLUSION

This study unveils gender differences in risk perception, health protective behaviors, vaccine hesitancy, and compliance with contact-tracing using a hypothetical viral pandemic. Gender-specific health education raising awareness of health protective behaviors may be beneficial to prevent future pandemics.

摘要

简介

严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2)感染会导致男性比女性出现更严重的症状和更高的死亡率。人们认为生物学性别在对 SARS-CoV-2 的免疫反应中起作用,这可以解释这种性别差异。然而,影响健康保护行为从而影响健康结果的性别因素的贡献仍未得到充分探索。

方法

我们使用来自 2019 年台湾社会变迁调查的假设性流感大流行数据,评估了性别在对 COVID-19 大流行的态度中的作用。参与者通过全国分层、三阶段概率比例抽样进行选择,以填写问卷,询问他们对假设性大流行的看法以及采取健康保护行为的意图。

结果

共纳入 1990 名参与者(中位数年龄 45.92 岁,49%为女性)。观察到显著的性别差异(p<0.001)。对大流行的风险感知(OR=1.28,95%CI [1.21-1.35],p<0.001)、年龄较大(OR=1.06,95%CI [1.05-1.07],p<0.001)、女性(OR=1.18,95%CI [1.09-1.27],p<0.001)、较高的教育程度(OR=1.10,95%CI [1.06-1.13],p<0.001)和更大的家庭规模(OR=1.09,95%CI [1.06-1.15],p<0.001)与健康保护行为呈正相关。对大流行的风险感知(OR=1.25,95%CI [1.15-1.36])、较高的教育程度(OR=1.07,95%CI [1.02-1.13],p<0.05)、已婚(OR=1.17,95%CI [1.01-1.36],p<0.05)和更大的家庭规模(OR=1.33,95%CI [1.25-1.42],p<0.001)与接种疫苗的意愿呈正相关。然而,与男性相比,女性的疫苗接种意愿(OR=0.85,95%CI [0.75-0.90],p<0.01)和接触者追踪的依从性(OR=0.95,95%CI [0.90-1.00],p<0.05)呈负相关。与孩子同住也与接种疫苗的意愿呈负相关(OR=0.77,95%CI [0.66-0.90],p<0.001)。

结论

本研究使用假设性病毒大流行数据揭示了风险感知、健康保护行为、疫苗犹豫和接触者追踪依从性方面的性别差异。提高对健康保护行为的认识的性别特定健康教育可能有助于预防未来的大流行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be4/9558414/c08512ef6b8f/12889_2022_14288_Fig1_HTML.jpg

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