Laboratorio Integral de Investigación en Alimentos, Tecnológico Nacional de México/Instituto Tecnológico de Tepic, Tepic, Nayarit, México.
Departamento de Estudios de Posgrado e Investigación, Tecnológico Nacional de México/Instituto Tecnológico de Tlajomulco, Tlajomulco de Zúñiga, Jalisco, Mexico.
Chem Biodivers. 2022 Nov;19(11):e202200806. doi: 10.1002/cbdv.202200806. Epub 2022 Nov 3.
This study aimed to microencapsulate the sea grape ethanolic extract by the spray drying process, characterizing the obtained powder, and evaluating its antimutagenicity activity. Microparticles showed a mean size of 6.28 μm and a spherical shape with a smooth surface. The powder had a low moisture content (4.02±0.92 %) and water activity (0.27±0.01), and high solubility (76±3.60 %). Moreover, hygroscopicity (14.75±2.63 g/100 g of powder) and bulk density (0.63±0.03 g/cm ) values suggested that this powder can be easily handled at a pilot or industrial scale. In addition, microencapsulation protected the extract against oxidation by ultraviolet light, improved its thermal stability, and its antimutagenicity activity was similar to fresh sea grape extract. In conclusion, the microencapsulation with maltodextrin by spray drying technique is an alternative to protect bioactive compounds from sea grapes against environmental conditions, maintaining their antimutagenic activity.
本研究旨在通过喷雾干燥工艺对海葡萄的乙醇提取物进行微胶囊化，对所得粉末进行表征，并评价其抗诱变活性。微颗粒的平均粒径为 6.28μm，呈球形，表面光滑。粉末的水分含量（4.02±0.92%）和水分活度（0.27±0.01）较低，溶解度（76±3.60%）较高。此外，吸湿性（14.75±2.63g/100g 粉末）和堆密度（0.63±0.03g/cm）表明，该粉末在中试或工业规模上很容易处理。此外，微胶囊化可防止提取物受到紫外线的氧化，提高其热稳定性，且其抗诱变活性与新鲜海葡萄提取物相似。总之，喷雾干燥技术用麦芽糊精对海葡萄的微胶囊化是保护生物活性化合物免受环境条件影响的一种替代方法，可保持其抗诱变活性。
