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在加利福尼亚州一个综合医疗保健系统中,在 COVID-19 大流行期间,按种族/民族和社会经济地位划分的 HPV 疫苗接种和 HPV 疫苗接种率的趋势。

Trends in HPV vaccine administration and HPV vaccine coverage in children by race/ethnicity and socioeconomic status during the COVID-19 pandemic in an integrated health care system in California.

机构信息

Department of Research and Evaluation, Kaiser Permanente, Pasadena, CA, USA.

Department of Pediatrics, Kaiser Permanente, Palmdale, CA 93552, USA.

出版信息

Vaccine. 2022 Nov 2;40(46):6575-6580. doi: 10.1016/j.vaccine.2022.09.073. Epub 2022 Oct 3.

Abstract

BACKGROUND

We sought to evaluate the trends of HPV vaccination between 03/2019-09/2021 and whether the impact of the COVID pandemic on HPV vaccination varied by race/ethnicity and neighborhood deprivation index (NDI).

METHODS

Electronic medical records at Kaiser Permanente Southern California were used to assess monthly volume of HPV vaccine doses administered among children aged 9-12.9yrs, and up-to-date coverage (% vaccinated) by age 13 between 03/2019-09/2021. Modified Poisson models were used to evaluate the interactions between race/ethnicity, NDI and the pandemic periods on HPV vaccine coverage.

RESULTS

HPV vaccine doses administered in 2020/2021 have returned to the 2019 level after the initial drop. The average up-to-date coverage in 05/2021-09/2021 (54.8%) remained lower than the pre-pandemic level (58.5%). The associations between race/ethnicity, NDI and HPV vaccine coverage did not vary due to the pandemic.

CONCLUSION

HPV vaccine promotion efforts are needed to address COVID-19 pandemic's lasting impact on HPV vaccination coverage.

摘要

背景

本研究旨在评估 2019 年 3 月至 2021 年 9 月期间 HPV 疫苗接种的趋势,并分析 COVID-19 大流行对 HPV 疫苗接种的影响是否因种族/族裔和社区剥夺指数(NDI)而有所不同。

方法

本研究使用 Kaiser Permanente Southern California 的电子病历,评估了 2019 年 3 月至 2021 年 9 月期间,9-12.9 岁儿童每月 HPV 疫苗剂量的接种情况,以及 13 岁时的最新接种率(%)。采用改良泊松模型评估种族/族裔、NDI 和大流行期间的相互作用对 HPV 疫苗接种率的影响。

结果

2020/2021 年 HPV 疫苗接种剂量在最初下降后已恢复到 2019 年的水平。2021 年 5 月至 9 月的平均最新接种率(54.8%)仍低于大流行前的水平(58.5%)。由于大流行,种族/族裔、NDI 和 HPV 疫苗接种率之间的关联没有变化。

结论

需要加强 HPV 疫苗推广力度,以解决 COVID-19 大流行对 HPV 疫苗接种率的持久影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dc6/9527222/e7208259248b/gr1_lrg.jpg

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