Department of Research and Evaluation, Kaiser Permanente, Pasadena, CA, USA.
Department of Pediatrics, Kaiser Permanente, Palmdale, CA 93552, USA.
Vaccine. 2022 Nov 2;40(46):6575-6580. doi: 10.1016/j.vaccine.2022.09.073. Epub 2022 Oct 3.
We sought to evaluate the trends of HPV vaccination between 03/2019-09/2021 and whether the impact of the COVID pandemic on HPV vaccination varied by race/ethnicity and neighborhood deprivation index (NDI).
Electronic medical records at Kaiser Permanente Southern California were used to assess monthly volume of HPV vaccine doses administered among children aged 9-12.9yrs, and up-to-date coverage (% vaccinated) by age 13 between 03/2019-09/2021. Modified Poisson models were used to evaluate the interactions between race/ethnicity, NDI and the pandemic periods on HPV vaccine coverage.
HPV vaccine doses administered in 2020/2021 have returned to the 2019 level after the initial drop. The average up-to-date coverage in 05/2021-09/2021 (54.8%) remained lower than the pre-pandemic level (58.5%). The associations between race/ethnicity, NDI and HPV vaccine coverage did not vary due to the pandemic.
HPV vaccine promotion efforts are needed to address COVID-19 pandemic's lasting impact on HPV vaccination coverage.
本研究旨在评估 2019 年 3 月至 2021 年 9 月期间 HPV 疫苗接种的趋势,并分析 COVID-19 大流行对 HPV 疫苗接种的影响是否因种族/族裔和社区剥夺指数(NDI)而有所不同。
本研究使用 Kaiser Permanente Southern California 的电子病历,评估了 2019 年 3 月至 2021 年 9 月期间,9-12.9 岁儿童每月 HPV 疫苗剂量的接种情况,以及 13 岁时的最新接种率(%)。采用改良泊松模型评估种族/族裔、NDI 和大流行期间的相互作用对 HPV 疫苗接种率的影响。
2020/2021 年 HPV 疫苗接种剂量在最初下降后已恢复到 2019 年的水平。2021 年 5 月至 9 月的平均最新接种率(54.8%)仍低于大流行前的水平(58.5%)。由于大流行,种族/族裔、NDI 和 HPV 疫苗接种率之间的关联没有变化。
需要加强 HPV 疫苗推广力度,以解决 COVID-19 大流行对 HPV 疫苗接种率的持久影响。