Clinical and Applied Psychology Unit, Department of Psychology, University of Sheffield, Cathedral Court Floor F, 1 Vicar Lane, Sheffield, S1 2LT, United Kingdom.
Clinical and Applied Psychology Unit, Department of Psychology, University of Sheffield, Cathedral Court Floor F, 1 Vicar Lane, Sheffield, S1 2LT, United Kingdom.
Behav Res Ther. 2022 Dec;159:104200. doi: 10.1016/j.brat.2022.104200. Epub 2022 Sep 17.
Early dropout hinders the effective adoption of brief psychological interventions and is associated with poor treatment outcomes. This study examined if attendance and depression treatment outcomes could be improved by matching patients to either face-to-face or computerized low-intensity psychological interventions.
Archival clinical records were analysed for 85,664 patients who accessed face-to-face or computerized guided self-help (GSH). The primary outcome was early dropout (attending ≤3 sessions). Supervised machine learning analyses were applied in a training sample (n = 55,529). The trained algorithm was cross-validated in an independent test sample (n = 30,135). The clinical utility of the model was evaluated using logistic regression, chi-square tests, and sensitivity analyses in a balanced subsample.
Patients who received their model-indicated treatment modality were 12% more likely to receive an adequate dose of treatment OR = 1.12 (95% CI = 1.02 to 1.24), p = .02, and the strength of this effect was larger in the balanced subsample (OR = 2.10, 95% CI = 1.65 to 2.68, p < .001). Patients had better treatment outcomes when matched to their model-indicated treatment modality.
Machine learning approaches may enable services to optimally match patients to the treatment modality that maximizes attendance.
早期辍学阻碍了简短心理干预的有效采用,并与治疗效果不佳有关。本研究旨在检验通过将患者匹配到面对面或计算机化的低强度心理干预,是否可以提高出勤率和抑郁治疗效果。
分析了 85664 名接受面对面或计算机化引导自助(GSH)的患者的档案临床记录。主要结局是早期辍学(参加 ≤3 次)。在训练样本(n=55529)中应用了监督机器学习分析。在独立测试样本(n=30135)中对经过训练的算法进行了交叉验证。使用逻辑回归、卡方检验和平衡子样本中的敏感性分析评估模型的临床实用性。
接受模型指示治疗方式的患者接受足够剂量治疗的可能性增加 12%(OR=1.12,95%CI=1.02 至 1.24),p=0.02,且在平衡子样本中这种效果更强(OR=2.10,95%CI=1.65 至 2.68,p<0.001)。当患者与模型指示的治疗方式匹配时,治疗效果更好。
机器学习方法可以使服务机构能够最佳地将患者匹配到最大限度提高出勤率的治疗方式。