Purdy Graeme M, Venner Chris P, Tandon Puneeta, McNeely Margaret L
Department of Physical Therapy, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Alberta, Canada.
Cross Cancer Institute, Edmonton, Canada.
Digit Health. 2022 Oct 11;8:20552076221129066. doi: 10.1177/20552076221129066. eCollection 2022 Jan-Dec.
eHealth exercise interventions have the unique ability to leverage the benefits of in-person programming (tailoring and supervision) with the benefits of home programming (flexibility). There may be a role for eHealth-delivered exercise for people with multiple myeloma (MM), as exercise tailoring and supervision are critical for successful outcomes due to the significant impacts/risks of myeloma-related side effects. The purpose of this study was to determine the safety, feasibility, and preliminary efficacy of a 12-week virtually supported eHealth exercise program.
Participants with MM completed a 12-week virtually supported home exercise program involving virtually supervised group workouts, independent workouts, and aerobic exercise. Tailoring was facilitated by the functionality of HEAL-Me, a novel eHealth app. Participants completed virtual fitness assessments and questionnaires at baseline and week 12.
Twenty-nine participants consented, 26 completed all follow-up testing (90%). Exercise adherence was 90% (group), 83% (independent), and 90% (aerobic). No serious adverse events (grade ≥3) occurred. Significant improvements were found for quality of life and physical fitness. There was a high level of program/app satisfaction: 96% of participants agreed or strongly agreed that the exercise program was beneficial, 93% found it enjoyable, 89% were satisfied or very satisfied with delivery through the HEAL-Me app, and 48% felt that the eHealth program helped them manage cancer-related symptoms and side-effects.
An eHealth intervention that is individually tailored and includes virtual supervision and active support from the healthcare team is feasible and acceptable to people with MM. The findings from this study warrant investigation using a large-scale randomized controlled trial.
电子健康运动干预具有独特的能力,能够将面对面训练(个性化定制和监督)的优势与家庭训练(灵活性)的优势结合起来。对于多发性骨髓瘤(MM)患者而言,电子健康运动可能会发挥作用,因为鉴于骨髓瘤相关副作用的重大影响/风险,运动的个性化定制和监督对于取得成功的结果至关重要。本研究的目的是确定一项为期12周的虚拟支持的电子健康运动计划的安全性、可行性和初步疗效。
MM患者完成了一项为期12周的虚拟支持的家庭运动计划,该计划包括虚拟监督的团体训练、独立训练和有氧运动。通过一款新型电子健康应用程序HEAL-Me的功能实现了个性化定制。参与者在基线和第12周完成了虚拟体能评估和问卷调查。
29名参与者同意参与研究,26名完成了所有随访测试(90%)。运动依从性分别为90%(团体训练)、83%(独立训练)和90%(有氧运动)。未发生严重不良事件(≥3级)。生活质量和体能有显著改善。对该计划/应用程序的满意度很高:96%的参与者同意或强烈同意该运动计划有益,93%的人觉得它有趣,89%的人对通过HEAL-Me应用程序进行的训练感到满意或非常满意,48%的人认为电子健康计划帮助他们管理了与癌症相关的症状和副作用。
一项经过个性化定制、包括虚拟监督以及医疗团队积极支持的电子健康干预措施对MM患者来说是可行且可接受的。本研究结果值得通过大规模随机对照试验进行进一步调查。