Rodgers Ellen, Marwaha Steven, Humpston Clara
Institute for Mental Health, School of Psychology, University of Birmingham, B15 2TT, Birmingham, UK.
Birmingham and Solihull Mental Health Foundation Trust, B1 3RB, Birmingham, UK.
J Eat Disord. 2022 Oct 18;10(1):150. doi: 10.1186/s40337-022-00664-0.
Psychotic disorders and eating disorders are complex mental illnesses associated with increased mortality and functional impairment. This study aimed to investigate the co-occurrence and relationships between eating disorders and psychotic disorders and assess the mediation effect of mood instability.
This study used data from the Adult Psychiatric Morbidity Survey (APMS) 2014, a general population-based survey in England. Participants (total N = 7546, female N = 4488, male N = 3058, mean age = 52.3 years) were categorised based on psychotic disorder status into the groups of probable psychosis, diagnosed psychosis, and healthy controls without psychosis. The dependent variable of this study was the presence or absence of an eating disorder, with mood instability as the mediator. Logistic regression and mediation analyses were conducted to assess the relationships between these variables.
Both probable and diagnosed psychoses were significantly related to the presence of an eating disorder, and mood instability was found to be a mediating variable with moderate effect.
The present study demonstrates a significant relationship between eating disorders and psychotic disorders in the English general population, indicating higher levels of co-occurrence between these two groups of disorders than when compared with healthy controls. The findings also suggest the relationship between eating and psychotic disorders is mediated, to an extent, by the presence of mood instability traits. Future research could extend the present study's findings through assessing whether specific eating disorders are more significantly related to psychotic disorders than others.
精神障碍和饮食失调是复杂的精神疾病,与死亡率增加和功能损害相关。本研究旨在调查饮食失调与精神障碍之间的共病情况及关系,并评估情绪不稳定的中介作用。
本研究使用了2014年成人精神病患病率调查(APMS)的数据,这是一项基于英国普通人群的调查。参与者(总数N = 7546,女性N = 4488,男性N = 3058,平均年龄 = 52.3岁)根据精神障碍状况被分为可能患有精神病、已确诊患有精神病和无精神病的健康对照组。本研究的因变量是饮食失调的存在与否,以情绪不稳定作为中介变量。进行逻辑回归和中介分析以评估这些变量之间的关系。
可能患有精神病和已确诊患有精神病均与饮食失调的存在显著相关,并且发现情绪不稳定是一个具有中等效应的中介变量。
本研究表明,在英国普通人群中,饮食失调与精神障碍之间存在显著关系,这表明这两组疾病的共病水平高于与健康对照组相比时的情况。研究结果还表明,饮食失调与精神障碍之间的关系在一定程度上是由情绪不稳定特征介导的。未来的研究可以通过评估特定的饮食失调是否比其他饮食失调与精神障碍的关系更显著来扩展本研究的结果。