Department of Neurology, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou, 313000 Zhejiang, China.
Orthopedics Department, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou, 313000 Zhejiang, China.
Comput Math Methods Med. 2022 Oct 14;2022:8284870. doi: 10.1155/2022/8284870. eCollection 2022.
To systematically assess the effect of nursing intervention on promoting the healing of refractory wounds (RW) in patients with diabetic foot (DF).
A computer search of PubMed, EMBASE, ScienceDirect, CochraneLibrary, China knowledge Network Database (CNKI), China VIP Database, Wanfang Database, and China Biomedical Literature Database (CBM) online database was conducted in a randomized controlled trial (RCT) of traditional Chinese and western medicine nursing intervention on patients with RW of DF. Retrieval time was limited to the period from the date the database was established to present. Separately, two researchers gathered the data. RevMan5.3 statistical software was used to analyze the collected data by meta-analysis according to Cochrane Handbook 5.3.
Finally, 8 articles were included with a total sample size of 772 cases. The meta-analysis of the wound healing time after intervention indicated that the wound healing time of the study group was notably shorter, and the difference was statistically significant ( < 0.05). Qualitative, fixed-effect model analysis indicated that the nursing effective rate after treatment in the study group was notably higher, and the difference was statistically significant ( < 0.05). Fasting blood glucose level in the study group after treatment was notably lower, and the difference was statistically significant ( < 0.05). The life quality in the study group was notably higher, and the difference was statistically significant ( < 0.05). Further subgroup analysis indicated that the score of physical function (PF), emotional function (RE), social function (SF), physical pain (BP), general health (GH), vitality (VT), and mental health (MH) in the study group were higher, and the difference was statistically significant ( < 0.05). A publication bias analysis was conducted using the inverted funnel chart as the outcome indicator for this study. The results indicated that most of the funnel maps were symmetrical and a few were asymmetrical, suggesting that there exhibited a certain publication bias in the included literature.
The application of traditional Chinese and western medicine nursing intervention when treating DF patients clinically can effectively promote the healing of foot ulcer wounds. Traditional Chinese and western medicine nursing can help patients heal wounds faster and enhance their life quality compared to simplistic western medicine nursing. According to the original literature, the conclusion deserves to be popularized in clinic.
系统评估护理干预对促进糖尿病足（DF）患者难治性创面（RW）愈合的效果。
计算机检索 PubMed、EMBASE、ScienceDirect、CochraneLibrary、中国知网数据库（CNKI）、中国维普数据库（VIP）、万方数据库和中国生物医学文献数据库（CBM）中关于中西医结合护理干预 DF 患者 RW 的随机对照试验（RCT），检索时限均为建库至当前。由 2 名研究者分别进行数据提取。采用 RevMan5.3 统计软件进行 meta 分析。
最终纳入 8 篇文献，共 772 例患者。干预后创面愈合时间的 meta 分析结果显示，研究组创面愈合时间明显缩短，差异有统计学意义（ < 0.05）。定性、固定效应模型分析结果显示，研究组治疗后的护理有效率明显更高，差异有统计学意义（ < 0.05）。治疗后研究组空腹血糖水平明显降低，差异有统计学意义（ < 0.05）。研究组生活质量明显更高，差异有统计学意义（ < 0.05）。进一步亚组分析结果显示，研究组的生理功能（PF）、情感功能（RE）、社会功能（SF）、躯体疼痛（BP）、一般健康状况（GH）、活力（VT）、精神健康（MH）评分均更高，差异有统计学意义（ < 0.05）。采用倒漏斗图作为本研究的结局指标进行发表偏倚分析，结果显示多数漏斗图基本对称，少数不对称，提示纳入文献存在一定发表偏倚。
临床上采用中西医结合护理干预治疗 DF 患者可有效促进足部溃疡伤口愈合，与单纯应用西药护理相比，中西医结合护理能帮助患者更快地愈合伤口，提高生活质量。基于原始文献，该结论值得在临床中推广。
