Virador Gabriel M, de Marcos Lola, Virador Victoria M
Biology Department, Montgomery College, Rockville, MD, USA.
University of Navarra, Pamplona, Navarra, Spain.
Methods Mol Biol. 2019;1879:221-241. doi: 10.1007/7651_2018_161.
This overview of the current state of skin wound healing includes in vitro and in vivo approaches along with some recent clinical trials. From an introduction to wound healing, to tissue engineering as applied to the skin, we cover the basis for the current wound care techniques as well as novel and promising approaches. Special emphasis is given to refractory wounds which include wounds in diabetic patients. Natural compounds have been ever present in wound healing, and so we devote a section to highlighting current attempts to understand their mechanisms and to use them in novel ways.
本文对皮肤伤口愈合的当前状态进行了概述，涵盖了体外和体内方法以及一些近期的临床试验。从伤口愈合的介绍到应用于皮肤的组织工程，我们阐述了当前伤口护理技术的基础以及新颖且有前景的方法。特别强调了难治性伤口，包括糖尿病患者的伤口。天然化合物一直存在于伤口愈合过程中，因此我们专门辟出一节来重点介绍目前在理解其作用机制以及以新方式应用它们方面所做的尝试。
