Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
Bureau of Infectious Disease Diagnosis Control, Korea Disease Control and Prevention Agency, Osong, Korea.
Ann Lab Med. 2023 Mar 1;43(2):137-144. doi: 10.3343/alm.2023.43.2.137. Epub 2022 Oct 25.
While the coronavirus disease 2019 pandemic is ongoing, monkeypox has been rapidly spreading in non-endemic countries since May 2022. Accurate and rapid laboratory tests are essential for identifying and controlling monkeypox. Korean Society for Laboratory Medicine and the Korea Disease Prevention and Control Agency have proposed guidelines for diagnosing monkeypox in clinical laboratories in Korea. These guidelines cover the type of tests, selection of specimens, collection of specimens, diagnostic methods, interpretation of test results, and biosafety. Molecular tests are recommended as confirmatory tests. Skin lesion specimens are recommended for testing in the symptomatic stage, and the collection of both blood and oropharyngeal swabs is recommended in the presymptomatic or prodromal stage.
虽然 2019 冠状病毒病疫情仍在持续,但自 2022 年 5 月以来,猴痘已在非流行国家迅速传播。准确快速的实验室检测对于识别和控制猴痘至关重要。韩国临床检验医学会和韩国疾病管理本部提出了韩国临床实验室猴痘诊断指南。这些指南涵盖了检测类型、标本选择、标本采集、诊断方法、检测结果解读和生物安全。建议使用分子检测作为确诊检测。推荐在症状期采集皮损标本进行检测,在潜伏期或前驱期建议同时采集血液和咽拭子。