Department of Biotechnology, National Institute of Pharmaceutical Education and Research, SAS Nagar, Mohali, Punjab-160062, India.
Trans R Soc Trop Med Hyg. 2023 Feb 1;117(2):67-71. doi: 10.1093/trstmh/trac100.
Visceral l eishmaniasis (VL), also known as kala-azar, had once been targeted for elimination in 2020, which now has been shifted to 2030. The year 2020 was also the year in which the world was gripped by the coronavirus disease 2019 (COVID-19) pandemic. This review sheds light on the impact of COVID-19 on VL elimination programmes and the increasing incidences of COVID-19/VL cases. Lockdowns were imposed worldwide that led to the suspension of surveys, active case finding and mass drug administration, which are important activities to manage neglected tropical diseases. Healthcare machinery was redirected to control the pandemic and acute resource shortages were seen. Budget cuts from funding agencies and donors also came as a severe blow. Priority changes for manufacturers of drugs and diagnostic kits have also exacerbated the situation. Cases where patients were co-infected with VL and COVID-19 were reported across various settings and in people of various age groups, posing unprecedented challenges in diagnosis and treatment. Concerted efforts from all stakeholders are required to understand and deal with the impact that this pandemic has had on VL.
内脏利什曼病(VL),也称为黑热病,原定于 2020 年消除,现已推迟至 2030 年。2020 年也是世界受到 2019 年冠状病毒病(COVID-19)大流行影响的一年。这篇综述探讨了 COVID-19 对 VL 消除规划和 COVID-19/VL 病例不断增加的影响。全球范围内实施了封锁措施,导致调查、主动病例发现和大规模药物治疗暂停,这些都是管理被忽视热带病的重要活动。医疗保健机构被重新引导以控制大流行,同时出现了严重的资源短缺。来自资金机构和捐助者的预算削减也造成了严重打击。药品和诊断试剂盒制造商的优先事项发生变化也使情况恶化。在不同环境和不同年龄组的人群中,都有 VL 和 COVID-19 合并感染的病例报告,这给诊断和治疗带来了前所未有的挑战。所有利益攸关方都需要共同努力,了解和应对这一大流行病对 VL 产生的影响。