Nemati Zargaran Fatemeh, Rostamian Mosayeb, Kooti Sara, Madanchi Hamid, Ghadiri Keyghobad
Infectious Diseases Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Behbahan Faculty of Medical Sciences, Behbahan, Iran.
Parasite Epidemiol Control. 2023 May;21:e00299. doi: 10.1016/j.parepi.2023.e00299. Epub 2023 Mar 30.
Co-infection of COVID-19 with other diseases increases the challenges related to its treatment management. COVID-19 co-infection with parasites is studied with low frequency. Here, we systematically reviewed the cases of parasitic disease co-infection with COVID-19. All articles on COVID-19 co-infected with parasites (protozoa, helminths, and ectoparasites), were screened through defined inclusion/exclusion criteria. Of 2190 records, 35 studies remained for data extraction. The majority of studies were about COVID-19 co-infected with malaria, followed by strongyloidiasis, amoebiasis, chagas, filariasis, giardiasis, leishmaniasis, lophomoniasis, myiasis, and toxoplasmosis. No or low manifestation differences were reported between the co-infected cases and naïve COVID-19 or naïve parasitic disease. Although there was a relatively low number of reports on parasitic diseases-COVID-19 co-infection, COVID-19 and some parasitic diseases have overlapping symptoms and also COVID-19 conditions and treatment regimens may cause some parasites re-emergence, relapse, or re-activation. Therefore, more attention should be paid to the on-time diagnosis of COVID-19 and the co-infected parasites.
新型冠状病毒肺炎（COVID-19）与其他疾病的合并感染增加了其治疗管理的挑战。对COVID-19与寄生虫的合并感染研究较少。在此，我们系统回顾了COVID-19合并寄生虫病的病例。所有关于COVID-19合并寄生虫（原生动物、蠕虫和外寄生虫）感染的文章均通过明确的纳入/排除标准进行筛选。在2190条记录中，有35项研究可供数据提取。大多数研究是关于COVID-19合并疟疾感染，其次是类圆线虫病、阿米巴病、恰加斯病、丝虫病、贾第虫病、利什曼病、滴虫病、蝇蛆病和弓形虫病。合并感染病例与单纯COVID-19病例或单纯寄生虫病病例之间未报告有明显或轻微的表现差异。尽管关于寄生虫病与COVID-19合并感染的报告数量相对较少，但COVID-19和一些寄生虫病有重叠症状，而且COVID-19的病情和治疗方案可能会导致一些寄生虫重新出现、复发或再激活。因此，应更加重视COVID-19和合并感染寄生虫的及时诊断。
