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放射组学:肿瘤微环境评估中当前应用和可能性的综述。

Radiomics: A review of current applications and possibilities in the assessment of tumor microenvironment.

机构信息

Department of Radiology, Lanzhou University Second Hospital, Chengguan District, Lanzhou, 730030, China; Second Clinical School, Lanzhou University, Lanzhou, 730030, China; Key Laboratory of Medical Imaging of Gansu Province, Lanzhou, 730030, China; Gansu International Scientific and Technological Cooperation Base of Medical Imaging Artificial Intelligence, Lanzhou, 730030, China.

Department of Radiology, Lanzhou University Second Hospital, Chengguan District, Lanzhou, 730030, China; Second Clinical School, Lanzhou University, Lanzhou, 730030, China; Key Laboratory of Medical Imaging of Gansu Province, Lanzhou, 730030, China; Gansu International Scientific and Technological Cooperation Base of Medical Imaging Artificial Intelligence, Lanzhou, 730030, China.

出版信息

Diagn Interv Imaging. 2023 Mar;104(3):113-122. doi: 10.1016/j.diii.2022.10.008. Epub 2022 Oct 22.

DOI:10.1016/j.diii.2022.10.008
PMID:36283933
Abstract

With the recent success in the application of immunotherapy for treating various advanced cancers, the tumor microenvironment has rapidly become an important field of research. The tumor microenvironment is complex and its characteristics strongly influence disease biology and potentially responses to systemic therapy. Accurate preoperative assessment of tumor microenvironment is of great significance for the formulation of an immunotherapy strategy and evaluation of patient prognosis. As a research hotspot in medical image analysis technology, radiomics has been applied in the auxiliary diagnosis of the tumor microenvironment. This article reviews the current status of radiomics in the elective application on tumor microenvironment and discusses potential prospects.

摘要

随着免疫疗法在治疗各种晚期癌症方面的应用取得成功,肿瘤微环境迅速成为一个重要的研究领域。肿瘤微环境复杂,其特征强烈影响疾病生物学和对全身治疗的潜在反应。准确的术前肿瘤微环境评估对免疫治疗策略的制定和患者预后的评估具有重要意义。作为医学影像分析技术的研究热点,放射组学已应用于肿瘤微环境的辅助诊断。本文综述了放射组学在肿瘤微环境选择性应用中的研究现状,并探讨了其潜在前景。

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