Luo Jing, Yu Huali, Lu Binyang, Wang Dehui, Deng Xu
Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu, 610054, P. R. China.
Shenzhen Institute for Advanced Study, University of Electronic Science and Technology of China, Shenzhen, 518110, P. R. China.
Small Methods. 2022 Dec;6(12):e2201106. doi: 10.1002/smtd.202201106. Epub 2022 Oct 26.
Superhydrophobic biological fluid-repellent surfaces (SBFRSs) have attracted great attention in the treatment of blood and urine-related diseases because of their unique wettability and compatibility, which creates a new path for the development of medical apparatus and instruments, and are expected to create advances in various fields. Here, this review provides an up-to-date summary of research progress on the repellent mechanism and application of SBFRSs. The underlying physical and chemical principles for designing superhydrophobic surfaces are first introduced. Then, the dialectical influences of solid-liquid interactions between superhydrophobic surfaces and biological fluids on the wettability and compatibility are emphatically expounded. Subsequently, attention is drawn to the recent applications of SBFRSs in biomedical fields, such as surgical medical apparatus, implant materials, extracorporeal circulation devices, and biological fluid detection. Finally, the outlook and challenges in terms of employing SBFRSs are also discussed. This review is expected to provide a comprehensive guidance for the preparation of SBFRSs with compatibility and long-term superhydrophobic stability that is closely related to clinical applications.
超疏水生物流体排斥表面(SBFRSs)因其独特的润湿性和兼容性,在血液和尿液相关疾病的治疗中备受关注,这为医疗器械和仪器的发展开辟了新途径,并有望在各个领域取得进展。在此,本综述提供了关于SBFRSs排斥机制和应用的最新研究进展总结。首先介绍了设计超疏水表面的基本物理和化学原理。然后,着重阐述了超疏水表面与生物流体之间的固液相互作用对润湿性和兼容性的辩证影响。随后,关注了SBFRSs在生物医学领域的最新应用,如外科医疗器械、植入材料、体外循环装置和生物流体检测。最后,还讨论了应用SBFRSs的前景和挑战。本综述有望为制备具有与临床应用密切相关的兼容性和长期超疏水稳定性的SBFRSs提供全面指导。