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基于碳纳米管场效应晶体管的化学和生物分析传感器。

Sensors Based on the Carbon Nanotube Field-Effect Transistors for Chemical and Biological Analyses.

机构信息

Department of Kidney Transplantation, The Second Xiangya Hospital of Central South University, Changsha 410011, China.

School of Life Sciences, Jiangsu University, Zhenjiang 212013, China.

出版信息

Biosensors (Basel). 2022 Sep 20;12(10):776. doi: 10.3390/bios12100776.

DOI:10.3390/bios12100776
PMID:36290914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9599861/
Abstract

Nano biochemical sensors play an important role in detecting the biomarkers related to human diseases, and carbon nanotubes (CNTs) have become an important factor in promoting the vigorous development of this field due to their special structure and excellent electronic properties. This paper focuses on applying carbon nanotube field-effect transistor (CNT-FET) biochemical sensors to detect biomarkers. Firstly, the preparation method, physical and electronic properties and functional modification of CNTs are introduced. Then, the configuration and sensing mechanism of CNT-FETs are introduced. Finally, the latest progress in detecting nucleic acids, proteins, cells, gases and ions based on CNT-FET sensors is summarized.

摘要

纳米生化传感器在检测与人类疾病相关的生物标志物方面发挥着重要作用，而由于其特殊的结构和优异的电子特性，碳纳米管 (CNTs) 已成为促进该领域蓬勃发展的重要因素。本文重点介绍了应用碳纳米管场效应晶体管 (CNT-FET) 生化传感器来检测生物标志物。首先，介绍了 CNTs 的制备方法、物理和电子特性以及功能修饰。然后，介绍了 CNT-FET 的结构和传感机制。最后，总结了基于 CNT-FET 传感器检测核酸、蛋白质、细胞、气体和离子的最新进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2560/9599861/d467c5a9955c/biosensors-12-00776-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2560/9599861/d467c5a9955c/biosensors-12-00776-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2560/9599861/cfcc712fce7e/biosensors-12-00776-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2560/9599861/3d5c55d934d2/biosensors-12-00776-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2560/9599861/7c4732a1be17/biosensors-12-00776-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2560/9599861/fd02bd7cc01f/biosensors-12-00776-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2560/9599861/309486e2faf9/biosensors-12-00776-g011.jpg
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