Orvoen-Frija E, Dore M F, Villoingt L, Benichou M, Fiessinger J N, Rochemaure J
Rev Pneumol Clin. 1987;43(3):138-44.
Pulmonary lesions of scleroderma are frequent, but little is known of their course, especially where lung function is concerned. We report the results of a longitudinal study performed in 32 patients with generalized scleroderma (ARA criteria) explored on at least 2 occasions with an interval of at least 24 months between the two examinations. Functional alterations seemed to be more pronounced in patients with severe Raynaud's syndrome, but in view of major individual variations no pathognomonic functional profile could be described.
硬皮病的肺部病变很常见，但对其病程了解甚少，尤其是在肺功能方面。我们报告了一项对32例全身性硬皮病（ARA标准）患者进行的纵向研究结果，这些患者至少接受了2次检查，两次检查之间间隔至少24个月。功能改变在重度雷诺综合征患者中似乎更为明显，但鉴于个体差异较大，无法描述出具有诊断意义的功能特征。
