Machut Katarzyna, Żółtowska Agata
Department of Conservative Dentistry, Faculty of Medicine, Medical University of Gdansk, 80-208 Gdansk, Poland.
J Clin Med. 2022 Oct 16;11(20):6092. doi: 10.3390/jcm11206092.
The study presents results of periapical lesion healing after one-visit root canal treatment (RCT) with Advanced Platelet Rich Fibrin plus (A-PRF+) application compared to a two-visit RCT with an inter-appointment calcium hydroxide filling. The comparison was made based on CBCT-Periapical Index (PAI) lesion volume changes and the occurrence of post endodontic pain. The results of 3D radiographic healing assessments based on volume reduction criteria were different from the CBCT-PAI. Based on volume changes, the healing assessment criteria-9 cases from the Study Group and six cases in the Control Group were defined as healed. Based on the CBCT-PAI healing assessment criteria, 8 cases from the Study Group and 9 cases from the Control Group were categorized as healed. The volumes of apical radiolucency were, on average, reduced by 85.93% in the Study Group and by 72.31% in the Control Group. Post-endodontic pain occurred more frequently in the Control than in the Study Group. The highest score of pain in the Study Group was five (moderate pain, n = 1), while in the Control Group, the highest score was eight (severe pain, n = 2). In the 6-month follow-up, CBCT scans showed a better healing tendency for patients in the Study Group.
该研究呈现了与采用就诊间氢氧化钙充填的两次就诊根管治疗（RCT）相比，单次就诊根管治疗（RCT）联合应用高级富血小板纤维蛋白加强型（A-PRF+）后根尖周病变愈合的结果。比较基于锥形束计算机断层扫描根尖周指数（PAI）病变体积变化以及根管治疗后疼痛的发生情况。基于体积减少标准的三维影像学愈合评估结果与CBCT-PAI不同。基于体积变化，研究组9例和对照组6例的愈合评估标准被定义为愈合。基于CBCT-PAI愈合评估标准，研究组8例和对照组9例被归类为愈合。研究组根尖透影区的体积平均减少了85.93%，对照组减少了72.31%。根管治疗后疼痛在对照组比研究组更频繁发生。研究组疼痛的最高评分为5分（中度疼痛，n = 1），而在对照组中，最高评分为8分（重度疼痛，n = 2）。在6个月的随访中，CBCT扫描显示研究组患者有更好的愈合趋势。
