孕期及分娩期间母胎血浆儿茶酚胺水平的研究。
The study of maternal and fetal plasma catecholamines levels during pregnancy and delivery.
作者信息
Wang L, Zhang W, Zhao Y
机构信息
Department of Obstetrics and Gynecology, 208th Hospital, Changchun, P. R. of China.
出版信息
J Perinat Med. 1999;27(3):195-8. doi: 10.1515/JPM.1999.027.
BACKGROUND
To study maternal and fetal plasma levels of catecholamines (CA) during pregnancy and delivery, especially changes in CA levels during fetal distress and conditions of different modes of delivery.
METHODS
Maternal and fetal plasma NE, E and DA levels were determined by high performance liquid chromatography (HPLC) for 16 non-pregnant women, 19 cases of early pregnancy, 17 cases of mid pregnancy, late pregnancy, spontaneous vaginal delivery and 53 cases of cesarean section.
RESULTS
Plasma NE and DA levels decreased gradually with the advance of gestational weeks, and levels of plasma NE were significantly lower than those of non-pregnant women (P < 0.05). The levels of plasma CA in patients who had elective cesarean section were significantly lower than those who had vaginal delivery and emergency cesarean section (P < 0.01). However, CA levels of the cord artery in the vaginal delivery group were significantly higher than those in the cesarean section group (P < 0.01).
CONCLUSION
Vaginal delivery is better than cesarean section for the newborn. If cesarean section is necessary, it is best for the newborn after onset of labor.
背景
研究孕期及分娩过程中母胎血浆儿茶酚胺（CA）水平，尤其是胎儿窘迫时及不同分娩方式下CA水平的变化。
方法
采用高效液相色谱法（HPLC）测定16名未孕女性、19例早孕、17例中孕、晚孕、自然阴道分娩及53例剖宫产患者母胎血浆去甲肾上腺素（NE）、肾上腺素（E）和多巴胺（DA）水平。
结果
血浆NE和DA水平随孕周增加逐渐降低，且血浆NE水平显著低于未孕女性（P<0.05）。择期剖宫产患者血浆CA水平显著低于阴道分娩和急诊剖宫产患者（P<0.01）。然而，阴道分娩组脐动脉CA水平显著高于剖宫产组（P<0.01）。
结论
阴道分娩对新生儿优于剖宫产。若有必要行剖宫产，最好在临产发动后进行。
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