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RNA 病毒、大流行和预期准备。

RNA Viruses, Pandemics and Anticipatory Preparedness.

机构信息

Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.

Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.

出版信息

Viruses. 2022 Sep 30;14(10):2176. doi: 10.3390/v14102176.

Abstract

RNA viruses are likely to cause future pandemics and therefore we must create and organize a deep knowledge of these viruses to prevent and manage this risk. Assuming prevention will fail, at least once, we must be prepared to manage a future pandemic using all resources available. We emphasize the importance of having safe vaccine candidates and safe broad-spectrum antivirals ready for rapid clinical translation. Additionally, we must have similar tools to be ready for outbreaks of RNA viruses among animals and plants. Finally, similar coordination should be accomplished for other pathogens with pandemic potential.

摘要

RNA 病毒很可能会引发未来的大流行,因此我们必须深入了解这些病毒,以预防和管理这种风险。假设预防措施会失败,至少有一次,我们必须准备好利用现有的所有资源来应对未来的大流行。我们强调必须准备好安全的疫苗候选物和安全的广谱抗病毒药物,以便快速进行临床转化。此外,我们还必须有类似的工具,为动植物中 RNA 病毒的爆发做好准备。最后,还应该为其他具有大流行潜力的病原体进行类似的协调。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2393/9611157/b1afa6e826e0/viruses-14-02176-g001.jpg

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