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能够靶向治疗并逆转耐药性的先进纳米颗粒可能是白血病治疗的曙光:一项文献计量学研究。

Advanced nanoparticles that can target therapy and reverse drug resistance may be the dawn of leukemia treatment: A bibliometrics study.

作者信息

Wang Rui, Zhao Changming, Jiang Shuxia, Zhang Zhaohua, Ban Chunmei, Zheng Guiping, Hou Yan, Jin Bingjin, Shi Yannan, Wu Xin, Zhao Qiangqiang

机构信息

Department of Hematology, Shandong Second Provincial General Hospital, Jinan, China.

Department of Hematology, The Qinghai Provincial People's Hospital, Xining, China.

出版信息

Front Bioeng Biotechnol. 2022 Oct 10;10:1027868. doi: 10.3389/fbioe.2022.1027868. eCollection 2022.

Abstract

With the development of nanomedicine, more and more nanoparticles are used in the diagnosis and treatment of leukemia. This study aimed to identify author, country, institutional, and journal collaborations and their impacts, assess the knowledge base, identify existing trends, and uncover emerging topics related to leukemia research. 1825 Articles and reviews were obtained from the WoSCC and analyzed by Citespace and Vosviewer. INTERNATIONAL JOURNAL OF NANOMEDICINE is the journal with the highest output. The contribution of FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY is also noteworthy. The three main aspects of research in Nanoparticles-leukemia-related fields included nanoparticles for the diagnosis and treatment of leukemia, related to the type and treatment of leukemia, the specific molecular mechanism, and existing problems of the application of nanoparticles in leukemia. In the future, synthesize nano-drugs that have targeted therapy and chemotherapy resistance according to the mechanism, which may be the dawn of the solution to leukemia. This study offers a comprehensive overview of the Nanoparticles-leukemia-related field using bibliometrics and visual methods for the first time, providing a valuable reference for researchers interested in Nanoparticles-leukemia.

摘要

随着纳米医学的发展,越来越多的纳米粒子被用于白血病的诊断和治疗。本研究旨在识别作者、国家、机构和期刊合作及其影响,评估知识基础,识别现有趋势,并揭示与白血病研究相关的新兴主题。从科学网核心合集(WoSCC)获取了1825篇文章和综述,并通过Citespace和Vosviewer进行分析。《国际纳米医学杂志》是发文量最高的期刊。《生物工程与生物技术前沿》的贡献也值得注意。纳米粒子 - 白血病相关领域的研究主要包括用于白血病诊断和治疗的纳米粒子,与白血病的类型和治疗、具体分子机制以及纳米粒子在白血病应用中的现存问题相关。未来,根据机制合成具有靶向治疗和化疗抗性的纳米药物,这可能是解决白血病问题的曙光。本研究首次使用文献计量学和可视化方法对纳米粒子 - 白血病相关领域进行了全面概述,为对纳米粒子 - 白血病感兴趣的研究人员提供了有价值的参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a261/9588980/ad26bc24f4f9/fbioe-10-1027868-g001.jpg

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