Wang Xing, Fan Qinyi, Li Yunyue, Xiao Junjian, Huang Yanyan, Guo Tiantian, Chen Hongguang, Li Mengqian
School of Life Sciences, Nanchang University, Nanchang, China.
Clinical Medical Experiment Center, Nanchang University, Nanchang, China.
Front Psychiatry. 2022 Oct 10;13:1010004. doi: 10.3389/fpsyt.2022.1010004. eCollection 2022.
Previous studies have showed that individuals infected with COVID-19 were more likely to report psychological symptoms. However, little is known about the changes from testing positive to negative to positive again.
This survey was conducted through the questionnaires including the 7-item Generalized Anxiety Disorder (GAD-7), the 9-item Patient Health Questionnaire (PHQ-9), as well as the Self-Rating Scale of Sleep (SRSS) to explore the psychological status of COVID-19 and re-positive cases.″re-positive″ is defined as a positive RT-PCR test at any time during the recovery period after testing negative.
A total of 94 COVID-19 patients presented the prevalence rates of anxiety, depression, insomnia, and any of the three psychological symptoms being 26.6, 8.6, 12.8, and 31.9%, respectively. Among these, 32 cases were re-tested positive during the recovery period, with the prevalence rates of anxiety, depression, insomnia, and any of the three psychological symptoms being 21.9, 18.7, 31.2, and 37.5%, respectively. The psychological status after re-positive showed a significant decrease in anxiety ( = 0.023), an increase in depression, and a significant rise in insomnia ( = 0.035). For those with no psychological symptoms during initial-positive, after re-positive, 5.88% reported anxiety, 5.88% reported depression, and 11.76% reported insomnia. For those who experienced only anxiety symptoms during initial-positive, after re-positive, 33.3% reported depression, and 33.3% reported insomnia.
Our findings encompassed the urgent concern for anxiety in initial-positive COVID-19 patients, depression in re-positive COVID-19 patients, and insomnia in both initial and re-positive patients, hence enabling targeted interventions for appeasing the psychological burden of COVID-19 patients.
先前的研究表明，感染新冠病毒的个体更有可能报告心理症状。然而，对于从检测呈阳性到阴性再到再次呈阳性的变化情况知之甚少。
本调查通过问卷进行，包括7项广泛性焦虑障碍量表（GAD-7）、9项患者健康问卷（PHQ-9）以及睡眠自评量表（SRSS），以探究新冠病毒感染者及复阳病例的心理状态。“复阳”定义为在检测呈阴性后的恢复期内任何时间点RT-PCR检测呈阳性。
共94例新冠病毒患者，焦虑、抑郁、失眠以及这三种心理症状中任一种的患病率分别为26.6%、8.6%、12.8%和31.9%。其中，32例在恢复期再次检测呈阳性，焦虑、抑郁、失眠以及这三种心理症状中任一种的患病率分别为21.9%、18.7%、31.2%和37.5%。复阳后的心理状态显示焦虑显著下降（P = 0.023），抑郁增加，失眠显著上升（P = 0.035）。对于初次检测呈阳性时无心理症状的患者，复阳后有5.88%报告有焦虑，5.88%报告有抑郁，11.76%报告有失眠。对于初次检测呈阳性时仅经历焦虑症状 的患者，复阳后有33.3%报告有抑郁，33.3%报告有失眠。
我们的研究结果包括对初次检测呈阳性的新冠病毒患者的焦虑、复阳的新冠病毒患者的抑郁以及初次和复阳患者的失眠的迫切关注，从而能够进行有针对性的干预，以减轻新冠病毒患者的心理负担。
