Ndukwe Chinedu Onwuka, Chiemeka Michael Emeka, Menkiti Felix Emeka, Ezejiofor Florence Ifeoma, Ike Gerald Kenechi, Chukwuanukwu Titus O
Department of Anatomic Pathology and Forensic Medicine, Faculty of Medicine, College of Health Sciences and Technology, Nnamdi Azikiwe University, Anambra State, Nigeria.
Department of Histopathology, Nnamdi Azikiwe University Teaching Hospital, Anambra State, Nigeria.
Oman Med J. 2022 Sep 30;37(5):e417. doi: 10.5001/omj.2022.07. eCollection 2022 Sep.
Albinism results from a deficiency of the protein responsible for melanin production in melanocytes. Albinos are at an increased risk of dermatoses and malignancies. Primary carcinosarcoma of the skin is an exceedingly rare biphasic tumor composed of malignant epithelial and mesenchymal elements with an unclear histogenesis. To our knowledge, this has not been reported in an African albino. Here, we report the index case of this rare tumor in an albino of African descent.
白化病是由黑素细胞中负责黑色素生成的蛋白质缺乏所致。白化病患者患皮肤病和恶性肿瘤的风险增加。原发性皮肤癌肉瘤是一种极其罕见的双相肿瘤，由恶性上皮和间充质成分组成，组织发生尚不清楚。据我们所知，非洲白化病患者中尚未有此报告。在此，我们报告了一例非洲裔白化病患者发生这种罕见肿瘤的索引病例。
