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Acute Glycemic Control in Prediabetes Individuals Favorably Alters Serum NLRP3 Inflammasome and Related Interleukins.糖尿病前期个体的急性血糖控制可改善血清 NLRP3 炎性小体及其相关白细胞介素。
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Elevated serum uric acid is a risk factor for progression to prediabetes in Japanese women: A 5-year retrospective chort study.血清尿酸升高是日本女性进展为糖尿病前期的危险因素:一项为期 5 年的回顾性队列研究。
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本文引用的文献

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Prevalence of diabetes mellitus and its relation with obesity in Turaif (Saudi Arabia) in 2017.2017年图赖夫(沙特阿拉伯)糖尿病患病率及其与肥胖的关系。
Electron Physician. 2017 Oct 25;9(10):5531-5535. doi: 10.19082/5531. eCollection 2017 Oct.
2
Prevalence of Prediabetes and Abdominal Obesity Among Healthy-Weight Adults: 18-Year Trend.健康体重成年人中糖尿病前期和腹型肥胖的患病率:18年趋势
Ann Fam Med. 2016 Jul;14(4):304-10. doi: 10.1370/afm.1946.
3
The Prevalence of Diabetes and Prediabetes in the Adult Population of Jeddah, Saudi Arabia--A Community-Based Survey.沙特阿拉伯吉达成年人口中糖尿病和糖尿病前期的患病率——一项基于社区的调查
PLoS One. 2016 Apr 1;11(4):e0152559. doi: 10.1371/journal.pone.0152559. eCollection 2016.
4
Type 2 Diabetes Mellitus in Saudi Arabia: Major Challenges and Possible Solutions.沙特阿拉伯的2型糖尿病:主要挑战与可能的解决方案
Curr Diabetes Rev. 2017;13(1):59-64. doi: 10.2174/1573399812666160126142605.
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Burden of Diabetes Mellitus in Saudi Arabia.沙特阿拉伯的糖尿病负担
Int J Health Sci (Qassim). 2015 Jul;9(3):V-VI. doi: 10.12816/0024690.
6
Diabetes Mellitus in Saudi Arabia: A Review of the Recent Literature.沙特阿拉伯的糖尿病:近期文献综述
Curr Diabetes Rev. 2016;12(4):359-368. doi: 10.2174/1573399811666150724095130.
7
Prediabetes diagnosis and treatment: A review.糖尿病前期的诊断与治疗:综述
World J Diabetes. 2015 Mar 15;6(2):296-303. doi: 10.4239/wjd.v6.i2.296.
8
Awareness of prediabetes--United States, 2005-2010.知晓前驱糖尿病——美国,2005-2010 年。
MMWR Morb Mortal Wkly Rep. 2013 Mar 22;62(11):209-12.
9
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.1990年和2010年20个年龄组中235种死因的全球和区域死亡率:全球疾病负担研究2010的系统分析
Lancet. 2012 Dec 15;380(9859):2095-128. doi: 10.1016/S0140-6736(12)61728-0.
10
Improved lifestyle and decreased diabetes risk over 13 years: long-term follow-up of the randomised Finnish Diabetes Prevention Study (DPS).改善生活方式可降低 13 年内的糖尿病风险:芬兰糖尿病预防研究(DPS)的长期随访。
Diabetologia. 2013 Feb;56(2):284-93. doi: 10.1007/s00125-012-2752-5. Epub 2012 Oct 24.

沙特阿拉伯艾卜哈市基层医疗中心成年患者的糖尿病前期患病率及相关危险因素评估:一项横断面研究

Prevalence of Prediabetes and Associated Risk Factor Assessment Among Adults Attending Primary Healthcare Centers in Al Bahah, Saudi Arabia: A Cross-Sectional Study.

作者信息

Alomari Abdullah, Al Hisnah Saad

机构信息

Public Health Sciences, Ministry of Health Holdings, Riyadh, SAU.

Public Health, Ministry of Health Holdings, Al Bahah, SAU.

出版信息

Cureus. 2022 Sep 22;14(9):e29465. doi: 10.7759/cureus.29465. eCollection 2022 Sep.

DOI:10.7759/cureus.29465
PMID:36299950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9587806/
Abstract

Background Prediabetes is an asymptomatic intermediate state of hyperglycemia with a major risk of developing type 2 diabetes (T2D). It is a progressive condition; it can take a few years for patients to become diabetic from a prediabetes state. Objectives This study aimed to detect the prevalence rate of prediabetes among the adult population and to assess the association of the risk factors to prediabetes in both the male and female genders. Methods A cross-sectional study was carried out in primary healthcare centers (PHC) in the city of Al Bahah, Saudi Arabia. A total of 378 study participants of both sexes from two central PHCs were eligible to participate in the study, which was conducted from January to February 2018. Data were collected through anthropometric measurements, laboratory investigations, and a predesigned questionnaire interview to identify demographic, lifestyle, and medical variables. Two blood tests were used to diagnose prediabetes: fasting plasma glucose (FBG) and hemoglobin A1c (HbA1C). Results The overall prevalence of prediabetes among all participants was 20% (around 21% in males and 19% in females of all ages). There was a statistically significant association between prediabetes and obesity (central obesity), hypertension, and a family history of diabetes mellitus (FHDM). Conclusion The prediabetic state is highly prevalent among adults attending PHC in Al Bahah city (20%). It is associated with obesity (especially central), hypertension, and FHDM. We highly recommend that public health professionals implement strategies for effective screening, diagnosis, and management of prediabetes.

摘要

背景

糖尿病前期是一种无症状的高血糖中间状态,具有发展为2型糖尿病(T2D)的主要风险。它是一种渐进性疾病;患者从糖尿病前期状态发展为糖尿病可能需要数年时间。

目的

本研究旨在检测成年人群中糖尿病前期的患病率,并评估男性和女性中糖尿病前期风险因素之间的关联。

方法

在沙特阿拉伯巴哈市的初级医疗保健中心(PHC)进行了一项横断面研究。2018年1月至2月,来自两个中心PHC的总共378名男女研究参与者有资格参与该研究。通过人体测量、实验室检查和预先设计的问卷调查收集数据,以确定人口统计学、生活方式和医学变量。使用两种血液检测来诊断糖尿病前期:空腹血糖(FBG)和糖化血红蛋白(HbA1C)。

结果

所有参与者中糖尿病前期的总体患病率为20%(各年龄段男性约为21%,女性约为19%)。糖尿病前期与肥胖(中心性肥胖)、高血压和糖尿病家族史(FHDM)之间存在统计学上的显著关联。

结论

在巴哈市就诊于PHC的成年人中,糖尿病前期状态非常普遍(20%)。它与肥胖(尤其是中心性肥胖)、高血压和FHDM有关。我们强烈建议公共卫生专业人员实施有效的糖尿病前期筛查、诊断和管理策略。