Gorasiya Amitkumar R, Mehta Hita H, Prakashey Arjun, Dave Manal
Department of Dermatology Venereology and Leprosy, Government Medical College, Bhavnagar, Gujarat, India.
Indian Dermatol Online J. 2022 Sep 5;13(5):600-605. doi: 10.4103/idoj.idoj_80_22. eCollection 2022 Sep-Oct.
Nailfold capillaroscopy (NFC) is a noninvasive quick method to visualize capillaries in the nailfold. There is paucity of these studies in healthy individuals in skin of color.
To evaluate the morphological characteristics and density of nailfold capillaries in healthy individuals.
This observational cross-sectional study was conducted in the Department of Dermatology at a tertiary care hospital. About 150 healthy individuals by consecutive sampling were included in the study.
A total of 150 healthy individuals aged between 20 and 60 years were enrolled from January 2021 to September 2021 after consenting to the study protocol and qualifying the inclusion and exclusion criteria. NFC was performed for various morphological parameters and mean capillary density was also calculated. Comparison was done in male vs female, age group 20-40 vs 41-60, and body mass index (BMI) <24.9 vs >25.
Different morphological parameters and capillary density were recorded and analyzed. The Mann-Whitney and Pearson's chi square was used according to type of data.
The study observed tortuous capillaries (45.33%), meandering capillaries (44.66%), neoangiogenesis (38.66%), plexus visibility (36.66%), dilated capillaries (33.33%), receding capillaries (31.33%), angulated capillaries (14.66%), and ramified capillaries (6.6%). The study found significantly decreased plexus visibility in those with BMI > 25.Tortuous and receding capillaries were significantly increased in age group >40 years.
Various capillary morphological findings can be present in normal individuals but their presence in more number of fingers should be considered to be pathological. This data on normal morphology and capillary density add to the physiological NFC findings and thus aid in identifying the abnormalities.
甲襞毛细血管镜检查（NFC）是一种可视化甲襞毛细血管的非侵入性快速方法。关于有色人种健康个体的此类研究较少。
评估健康个体甲襞毛细血管的形态特征和密度。
本观察性横断面研究在一家三级护理医院的皮肤科进行。通过连续抽样纳入了约150名健康个体。
2021年1月至2021年9月，在150名年龄在20至60岁之间的健康个体同意研究方案并符合纳入和排除标准后将其纳入研究。对各种形态学参数进行NFC检查，并计算平均毛细血管密度。在男性与女性、20 - 40岁年龄组与41 - 60岁年龄组以及体重指数（BMI）<24.9与>25之间进行比较。
记录并分析不同的形态学参数和毛细血管密度。根据数据类型使用曼 - 惠特尼检验和皮尔逊卡方检验。
该研究观察到迂曲毛细血管（45.33%）、蜿蜒毛细血管（44.66%）、新生血管形成（38.66%）、血管袢可见性（36.66%）、扩张毛细血管（33.33%）、退缩毛细血管（31.33%）、成角毛细血管（14.66%）和分支毛细血管（6.6%）。研究发现BMI>25者的血管袢可见性显著降低。年龄>40岁组的迂曲和退缩毛细血管显著增加。
正常个体可能存在各种毛细血管形态学表现，但如果在多个手指出现则应考虑为病理性。这些关于正常形态和毛细血管密度的数据补充了生理性NFC检查结果，从而有助于识别异常情况。
