Kawaoi A, Moriyama S
Acta Pathol Jpn. 1987 Jun;37(6):965-73. doi: 10.1111/j.1440-1827.1987.tb00446.x.
DIPN induced localized lesions of the rat thyroid gland are described histologically and classified into three major types: type 1, foci of cellular alteration; type 2, proliferative nodules; and type 3, overt carcinomas. Follicular, papillary and mixed papillofollicular subtypes are recognized in the type 2 lesions, and follicular, papillary, anaplastic and mixed subtypes in the type 3 lesions. The nature of the individual lesions is discussed.
组织学描述了二异丙基萘（DIPN）诱导的大鼠甲状腺局部病变，并将其分为三种主要类型：1型，细胞改变灶；2型，增生性结节；3型，明显的癌。在2型病变中可识别出滤泡型、乳头型和混合乳头滤泡型亚型，在3型病变中可识别出滤泡型、乳头型、间变性和混合型亚型。讨论了个体病变的性质。
