Emont S L, Cummings K M
Addict Behav. 1987;12(2):151-5. doi: 10.1016/0306-4603(87)90021-9.
This study examined nicotine dependence as a factor in weight gain following smoking cessation in a group of 104 recent ex-smokers. Nicotine dependence was measured using the eight-item Fagerstrom Tolerance Questionnaire. Findings support the hypothesis that weight gain following smoking cessation is greater among more nicotine dependent persons. Heavier smokers (greater than or equal to 26 cigs/day), those who reported smoking when they are ill, and those who reported smoking their first cigarette of the day within 30 minutes of waking up reported the greatest increases in weight one month after quitting. Twenty subjects reported using nicotine gum to help them quit smoking. A significant inverse correlation (r = -.17) was found between weight gain and the number of pieces of nicotine gum chewed per day. Stratification by the number of cigarettes smoked daily (greater than or equal to 26 cigs/versus less than 26 cigs/day) indicated that the correlation between weight gain and the number of pieces of nicotine gum chewed per day was significant only for heavy smokers (r = -.37 versus r = -.08). This finding suggests that nicotine replacement may help prevent weight gain following smoking cessation, especially for the more dependent smokers.
本研究在104名近期戒烟者中，考察了尼古丁依赖作为戒烟后体重增加的一个因素。使用八项法格斯特罗姆耐受问卷来测量尼古丁依赖。研究结果支持了这样一个假设，即尼古丁依赖程度越高的人，戒烟后的体重增加幅度越大。重度吸烟者（每天吸烟大于或等于26支）、那些报告在生病时吸烟的人，以及那些报告在醒来后30分钟内吸第一支烟的人，在戒烟一个月后体重增加最多。20名受试者报告使用尼古丁口香糖来帮助他们戒烟。体重增加与每天咀嚼的尼古丁口香糖片数之间存在显著的负相关（r = -0.17）。按每日吸烟量（大于或等于26支/天与小于26支/天）分层表明，体重增加与每天咀嚼的尼古丁口香糖片数之间的相关性仅在重度吸烟者中显著（r = -0.37对r = -0.08）。这一发现表明，尼古丁替代疗法可能有助于预防戒烟后的体重增加，尤其是对于依赖性更强的吸烟者。
