Liu Chunhua, Chen Xiang, Wu Simin
Department of Cancer Rehabilitation, Lishui Hospital of Traditional Chinese Medicine, Affiliated to Zhejiang University of Traditional Chinese Medicine, Lishui, Zhejiang, China.
The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Complement Ther Med. 2022 Dec;71:102892. doi: 10.1016/j.ctim.2022.102892. Epub 2022 Oct 26.
Findings on the usefulness of massage therapy (MT) in postoperative pain management are often inconsistent among studies.
This study's aim is to conduct a meta-analysis of randomized controlled trials (RCT) to clarify the effects of massage therapy in the treatment of postoperative pain.
Three databases (PubMed, Embase, and Cochrane Central Register of Controlled Trials) were searched for RCTs published from database inception through January 26, 2021. The primary outcome was pain relief. The quality of RCTs was appraised with the Cochrane Collaboration risk of bias tool. The random-effect model was used to calculate the effect sizes and standardized mean difference (SMD) with 95 % confidential intervals (CIs) as a summary effect. The heterogeneity test was conducted through I. Subgroup and sensitivity analyses were used to explore the source of heterogeneity. Possible publication bias was assessed using visual inspection of funnel plot asymmetry.
The analysis included 33 RCTs and showed that MT is effective in reducing postoperative pain (SMD, -1.32; 95 % CI, -2.01 to -0.63; p = 0.0002; I = 98.67 %). A similar significant effect was found for both short (immediate assessment) and long terms (assessment performed 4-6 weeks after the MT). Remarkably, we found neither the duration per session nor the dose had an impact on the effect of MT and there seemed to be no difference in the effects of different MT types. In addition, MT seemed to be more effective for adults. Furthermore, MT had better analgesic effects on cesarean section and heart surgery than orthopedic surgery.
Publication bias is possible due to the inclusion of studies in English only. Additionally, the included studies were extremely heterogeneous. Double-blind research on MT is difficult to implement, and none of the included studies is double-blind. There was some heterogeneity and publication bias in the included studies. In addition, there is no uniform evaluation standard for the operation level of massage practitioners, which may lead to research implementation bias.
MT is effective in reducing postoperative pain in both short and long terms.
关于按摩疗法(MT)在术后疼痛管理中的有效性,各项研究结果往往不一致。
本研究旨在对随机对照试验(RCT)进行荟萃分析,以阐明按摩疗法在治疗术后疼痛方面的效果。
检索了三个数据库(PubMed、Embase和Cochrane对照试验中央注册库),查找从数据库建立至2021年1月26日发表的RCT。主要结局是疼痛缓解。使用Cochrane协作偏倚风险工具评估RCT的质量。采用随机效应模型计算效应量和标准化均数差(SMD),并以95%置信区间(CI)作为汇总效应。通过I²进行异质性检验。采用亚组分析和敏感性分析探索异质性来源。通过观察漏斗图不对称性评估可能存在的发表偏倚。
该分析纳入了33项RCT,结果显示MT在减轻术后疼痛方面有效(SMD,-1.32;95%CI,-2.01至-0.63;p = 0.0002;I² = 98.67%)。在短期(即时评估)和长期(MT后4 - 6周进行评估)均发现了类似的显著效果。值得注意的是,我们发现每次治疗的时长和剂量均对MT的效果没有影响,而且不同类型的MT效果似乎没有差异。此外,MT对成年人似乎更有效。此外,MT在剖宫产和心脏手术中的镇痛效果优于骨科手术。
由于仅纳入了英文研究,可能存在发表偏倚。此外,纳入的研究异质性极高。对MT进行双盲研究难以实施,且纳入的研究均非双盲。纳入的研究存在一定的异质性和发表偏倚。此外,对于按摩从业者的操作水平没有统一的评估标准,这可能导致研究实施偏倚。
MT在短期和长期均能有效减轻术后疼痛。