Muniyandi Kasipandi, Jagadeesan Gayathri, George Blassan P, Manoharan Ashwini Lydia, Nataraj Gayathri, Abrahamse Heidi, Thangaraj Parimelazhagan
Bioprospecting Laboratory, Department of Botany, Bharathiar University, Coimbatore, Tamil Nadu 641-046 India.
Laser Research Centre, University of Johannesburg, Johannesburg, South Africa.
Food Sci Biotechnol. 2022 Sep 16;31(13):1717-1728. doi: 10.1007/s10068-022-01162-4. eCollection 2022 Dec.
A rich source of nutrients, figs have a number of clinically validated benefits. This study aimed to evaluate the in vitro simulated gastrointestinal digestion, and the antidiabetic and anticancer activity of (FMP) and (FRP) fruits polysaccharides. The pre-digested FMP revealed higher sugar content (721 ± 14.81 mg glucose equivalents/g sample) than FRP. After in vitro digestion, isolated fruit polysaccharides showed effective uptake with over 80% sugar loss. Free radicals and enzymatic inhibition after gastric digestion have been significantly modified, demonstrating the effective absorption of FMP and FRP through the intestine. Conversely, after the continuous digestion, the nutritional content of the isolated polysaccharides was gradually decreased compared to the pre-digested sample. At 30 µg/mL concentration of FMP and FRP was inhibited by 50% of breast cancer cells. The present study reveals the potential uptake of FMP and FRP as nutritional supplements in the future.
无花果富含营养，有许多经临床验证的益处。本研究旨在评估无花果果实多糖（FMP）和榕果多糖（FRP）的体外模拟胃肠道消化情况以及抗糖尿病和抗癌活性。预消化的FMP显示出比FRP更高的糖含量（721±14.81毫克葡萄糖当量/克样品）。体外消化后，分离出的果实多糖显示出有效摄取，糖损失超过80%。胃消化后的自由基和酶抑制作用有显著改变，表明FMP和FRP通过肠道有效吸收。相反，连续消化后，与预消化样品相比，分离出的多糖的营养成分逐渐降低。在30微克/毫升的浓度下，FMP和FRP对乳腺癌细胞的抑制率为50%。本研究揭示了FMP和FRP未来作为营养补充剂的潜在摄取情况。
