加强自噬与帕金森病之间的联系。
Strengthening the link between mitophagy and Parkinson's disease.
机构信息
MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK.
出版信息
Brain. 2022 Dec 19;145(12):4154-4156. doi: 10.1093/brain/awac405.
Abstract
This scientific commentary refers to ‘Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci’ by Soutar . (https://doi.org/10.1093/brain/awac325); and ‘DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy’ by Imberechts (https://doi.org/10.1093/brain/awac313).
摘要
这篇科学评论提到了 Soutar 的“NSL 复合物对帕金森病 16q11.2 和 MAPT H1 基因位点的调控作用”（https://doi.org/10.1093/brain/awac325）和 Imberechts 的“DJ-1 是 PINK1/parkin 依赖性线粒体自噬的必需下游介质”（https://doi.org/10.1093/brain/awac313）。
Zotero 插件